STUDY OF VIRULENCE FACTORS AND ANTIMICROBIAL SUSCEPTIBILITY PATTERN OF UROPATHOGENIC ESCHERICHIA COLI IN A TERTIARY CARE HOSPITAL
- Senior Resident-Department of Microbiology Hamdard Institute of Medical Sciences and Research,New Delhi.
- Assistant Professor-Department of Microbiology Gayatri Vidya Parishad Institute of Health Care and Medical Technology,Visakhapatnam, Andhra Pradesh.
- Senior Resident- Department of Microbiology All India Institute of Medical Sciences, Mangalgiri.
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Introduction:-Escherichia coli is the major causative agent of urinary tract infections. UPEC possess a variety of virulence factors that enable it to colonize, invade and persist within the urinary tract, leading to both complicated and uncomplicated UTIs. Knowledge of virulence factors of Escherichia coli is responsible for pathogenesis of UTIs and their antimicrobial susceptibility pattern will help in better understanding of the treatment of UTI. Emergence and spread of multi drug resistant strains of Escherichia coli have raised considerable interest in understanding their diversity and epidemiology of infections in humans.
Aim:To determine the virulence factors and antimicrobial susceptibility pattern of Uro Pathogenic Escherichia coli.
Materials and Methods:-A prospective study is done on urine samples over a period of 3 months from May 2025 to July 2025 in a tertiary care hospital to detect virulence factors like Hemolysis, Haemagglutination and Gelatin hydrolysis. Antibiotic susceptibility test was done by Kirby Baur disc diffusion method as per the CLSI guidelines.
[Mounica Pedapalli, Sivva V Kameswari Ramya and Nama Padmaja (2025); STUDY OF VIRULENCE FACTORS AND ANTIMICROBIAL SUSCEPTIBILITY PATTERN OF UROPATHOGENIC ESCHERICHIA COLI IN A TERTIARY CARE HOSPITAL Int. J. of Adv. Res. (Dec). 896-901] (ISSN 2320-5407). www.journalijar.com
SENIOR RESIDENT
India
