HEPATOPROTECTIVE EFFECT OF KALMEGHA (ANDROGRAPHIS PANICULATA): INSIGHTS FROM AN ANIMAL EXPERIMENTAL STUDY

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Background: Liver diseases are a global health burden. Kalmegha (Andrographis paniculata), a traditional medicinal plant, has been used for liver ailments, but scientific validation in experimental models is essential.

Objective: To evaluate the hepatoprotective potential of Kalmegha in experimentally induced hepatic injury in animal models.

Methods: [Briefly mention model used,e.g.,carbon tetrachloride/paracetamol-induced hepatotoxicity, animal group division, dose of extract, duration, biochemical & histopathological assessment.

Results: Kalmegha significantly improved biochemical parameters (ALT, AST, Bilirubin) and restored antioxidant levels compared to toxicant control. Histopathological examination supported biochemical findings. Conclusion: Findings suggest Kalmegha possesses promising hepatoprotective activity and may serve as a potential natural hepatoprotective agent.


[Barkha Thakur, Pankaj Mishra and Shiromani Mishra (2026); HEPATOPROTECTIVE EFFECT OF KALMEGHA (ANDROGRAPHIS PANICULATA): INSIGHTS FROM AN ANIMAL EXPERIMENTAL STUDY Int. J. of Adv. Res. (Jan). 863-868] (ISSN 2320-5407). www.journalijar.com


Dr Barkha Thakur ,Dr Pankaj Mishra,Dr Shiromani Mishra

India

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Article DOI: 10.21474/IJAR01/22618      
DOI URL: https://dx.doi.org/10.21474/IJAR01/22618