SOLITARY FIBROUS TUMOR OF THE VAGINAMIMICKING LEIOMYOMA: ARARE CASE REPORT

Background: Solitary fibrous tumor(SFT)is an uncommon mesenchymal neoplasm, most frequently arising from the pleura. Involvement of the female genital tract is rare, and vaginallocalization is exceptionally uncommon, posing significant diagnostic challenges.

Case summary: A 20-year-old girl presented with dysuria, haematuria, lower back pain, fever, and vaginal bleeding. Examination revealed a 6-8 cm firm, fixed, non-tender mass in the right lateral vaginal wall. Imaging suggested a vascular heterogeneous mass consistent with vaginal leiomyoma.She underwent complete surgical excision.Histopathology showed a well-circumscribed spindle-cell tumor with hyalinized collagen,lymphocytic infiltration,and characteristic staghorn vasculature, without mitosis or necrosis, confirming a solitary fibrous tumor. The postoperative course was uneventful.

Conclusion: Vaginal SFT should be considered in the differential diagnosis of spindle cell vaginal tumors. Accurate diagnosis relies on characteristic histomorphology and confirmatory immunohistochemistry,particularly STAT6.Complete surgical excision and long term follow-up are essential.