APPLICATION OF AMMONIA SENSORS IN ENDOSCOPY SYSTEMS FOR EARLY DETECTION OF HELICOBACTER PYLORI INFECTION

H. pylori infection is one of the major causes that lead to the early diagnosis of gastritis and cancer. The main objective of this work was to present the integration of the ammonia sensor into endoscopes, which can be used for the local and real-time detection of H. pylori infection. For this purpose, the ammonia sensor was considered due to the fact that the amount of NH3, which is produced by the activity of the urease enzyme, accurately reflects the presence of the infection, since the amount measured in the H. pylori positive samples differs significantly from the amount measured in the negative samples. The suggested sensor device includes the integration of the module into the distal end, which can provide stable gas molecule detection due to the presence of the selective semiconductor membrane in the acidic environment. The application of artificial intelligence-based processing of the real-time signal can lead to the automatic identification of the infection. The suggested method can provide improved accuracy in the diagnosis of the samples, even if the biopsy was not taken, thus speeding up the process and providing additional support for the early diagnosis of gastritis.