RADIOTHERAPY IN ADULT MEDULLOBLASTOMA WITH SYNCHRONOUS DROP METASTASIS: A CASE REPORT
Nisrine El Hayel
, Kaoutar Soussy
, Mohamed El Baraka
, Wissal Hassani
, Samia Khalfi
, Fatima Zahra Farhane
, Zenab Alami
and Touria Bouhafa
- Department of Radiotherapy, Oncology Hospital, Hassan II University Hospital, Fez, Morocco.
- Faculty of Medicine and Pharmacy, Sidi Mohammed Ben-Abdellah University, Fez, Morocco.
- Abstract
- Keywords
- How to Cite This Article
- Corresponding Author
Background: Adult medulloblastoma is a rare, fast-growing cancerous tumor, and synchronous spinal metastasis at diagnosis represents an uncommon and high-risk presentation. Evidence guiding management in adults remains limited, with most therapeutic strategies extrapolated from pediatric protocols.
Case presentation: We report the case of a 24-year-old patient with medulloblastoma presenting with neuraxial dissemination at initial staging. Magnetic resonance imaging confirmed a posterior fossa mass with synchronous spinal drop metastasis.
Treatment and outcome: The patient underwent a multimodal therapeutic approach centered on craniospinal irradiation. Radiotherapy was delivered to the entire neuraxis followed by targeted boosts to sites of macroscopic disease, using conformal techniques to ensure adequate coverage while respecting organ-at-risk constraints. Treatment was well tolerated and resulted in sustained complete remission at follow-up.
Nisrine El Hayel, Kaoutar Soussy, Mohamed El Baraka, Wissal Hassani, Samia Khalfi, Fatima Zahra Farhane, Zenab Alami and Touria Bouhafa (2026); RADIOTHERAPY IN ADULT MEDULLOBLASTOMA WITH SYNCHRONOUS DROP METASTASIS: A CASE REPORT, Int. J. of Adv. Res., 14 (02), 826-831, ISSN 2320-5407. DOI URL: https://dx.doi.org/10.21474/IJAR01/22800
Department of Radiotherapy, Oncology Hospital, Hassan II University Hospital,Faculty of Medicine and Pharmacy, Sidi Mohammed Ben-Abdellah University, Fez, Morocco.
Morocco
