Antimicrobial activity of Rhizospheric Bacteria of Curcuma longa Producing Metabolites against Human Bacterial Pathogens.

Medicinal plants are widely used all over the world for natural medicines. Curcuma longa are known as “mother medicine of nature”; they have chemical compounds for curing and preventing diseases. These plants have valuable antimicrobial resources and can produce a large number of metabolites which having antibacterial properties, regulating their own growth and development to encourage other organism beneficial to them and suppress organisms that are harmful. Soil microorganism provides an excellent resource for isolation and identification of therapeutically important products; Antimicrobial metabolites were produced by different bacteria present in soil. In present study 22 rhizospheric soil samples of Curcuma longa were collected from western Vidharbh region of Maharashtra state and were analyzed for presence of bacteria which can produce metabolites, isolation of desired bacteria were carried out by serial dilution method, Total 26 bacteria have been isolated from rhizospheric soil samples and out of 26 only 3 were potent isolates whose have been characterized on the basis of antibiogram test that revealed the activity of isolates, further characterization was done by following the Bergey’s Manual of Systematic Bacteriology. Accordingly Curcuma longa rhizospheric characterized isolates were Bacillus megatherium, Pseudomonas fluorescens and Globicatella sulfidifaciens. These potent isolates could be further exploited for the production of metabolites in production media.