UNLOCKING THE ANTICANCER EFFICACY OF 4-HYDROXY-3-METHOXY CINNAMIC ACID: A PREDICTIVE COMPUTATIONAL STUDY FOR DRUG DEVELOPMENT
Nitin Deshmukh
, Shruti Yadav
, Soumya Sahu
, Pranjal Patidar
, Saniya Karma
, Sumit Rathore
and Prabhat Kumar Das
- Department of Pharm. Chemistry, GRY Inst. of Pharmacy, Borawan, Khargone.
- Department of Pharmacognosy, GRY Inst. of Pharmacy, Borawan, Khargone.
- Abstract
- Keywords
- How to Cite This Article
- Corresponding Author
Background: Cancer remains a significant global health challenge, high failure rate in oncology therapeutic development necessitates novel approaches to model drug response and resistance. 4-Hydroxy-3-methoxy cinnamic acid (FA) is naturally occurring phenolic compounds found in various plants, have demonstrated significant in vitro and in vivo anticancer potential by targeting multiple molecular pathways, including apoptosis induction, tyrosine kinase inhibitor and cell cycle arrest.
Objective: This study utilizes a sophisticated computational study approaches docking simulations were, to investigate the molecular interactions and mechanisms by which 4-Hydroxy-3-methoxy cinnamic acid derivative exert their anticancer activities, focusing on predicting drug responses as anticancer or identifying novel biomarkers.
Nitin Deshmukh et, al (2026); UNLOCKING THE ANTICANCER EFFICACY OF 4-HYDROXY-3-METHOXY CINNAMIC ACID: A PREDICTIVE COMPUTATIONAL STUDY FOR DRUG DEVELOPMENT, Int. J. of Adv. Res., 14 (04), 707-722, ISSN 2320-5407. DOI URL: https://dx.doi.org/10.21474/IJAR01/23241
Department of Pharmacognosy, GRY Inst. of Pharmacy, Borawan, Khargone.
India
