ROSUVASTATIN FENOFIBRATE-INDUCED GASTROINTESTINAL DISTRESS: A CASE REPORT

Background: The combination of rosuvastatin and fenofibrate is highly effective for mixed dyslipidemia but is associated with a range of gastrointestinal (GI) side effects. While nausea and vomiting are common, severe abdominal distension can mimic serious conditions like acute pancreatitis or hepatotoxicity. Case Presentation: We report the case of a patient N.R. 49 years of female who presented with loss of apetite, persistent nausea, vomiting, and significant abdominal distension within a weeks time after initiating Rosuvas-F 10 (Rosuvastatin 10mg / Fenofibrate 160mg). Laboratory investigations were performed to rule out systemic complications. Symptoms resolved promptly within 3-7 days of drug discontinuation (de-challenge).