30Sep 2015

SYNTHESIS OF NOVEL THIAZOLIDINONES AND THEIR BIOLOGICAL ACTIVITIES

  • Department of Chemistry, B.K.M. Science College, Valsad, 396001, Gujarat (India)
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Various Novel 2-(Substitutedphenyl) -3-(2-(1-hydroxycyclohexyl)-2-(4-methoxyphenyl) ethyl)-2-phenylthiazolidin-4-one (2b) were prepared by refluxing with Schiff bases (2a) in presence of thioglycolic acid in benzene. The Schiff bases were prepared by condensation of various Aryl Aldehydes with 1-[2-amino-1-(3-methoxyphenyl)ethyl]cyclohexanol. The titled Compounds were characterized by TLC and spectral analysis. Some of the synthesized compounds showed potential antibacterial and antifungal activity.

[NOOSRAT KORTIWALA, JITESH PATEL AND VIKAS DESAI (2015); SYNTHESIS OF NOVEL THIAZOLIDINONES AND THEIR BIOLOGICAL ACTIVITIES Int. J. of Adv. Res. 3 (Sep). 971-976] (ISSN 2320-5407). www.journalijar.com

Noosrat Kortiwala

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