Higher Neutrophil/Lymphocyte ratio is a reliable laboratory marker for predicting the lower rate of complete revascularization following primary percutaneous coronary intervention

Introduction: There is a growing recognition that neutrophil / lymphocyte (N/L) ratio can provide a reliable inflammatory index as an estimation of the reperfusion success in the coronary artery disease. Aim of this study is to estimate if a meaningful relationship exists between neutrophil / lymphocyte ratio and the success of coronary reperfusion after primary percutaneous coronary intervention. Patients and Methods: 47 adult patients were included in the study. They were classified into 2 groups based on post intervention thrombolysis in myocardial infarction (TIMI): Group 1 with sufficient reperfusion (TIMI III, TIMI II) and Group 2 with insufficient reperfusion (TIMI 0, TIMI I). All the 47 patients had undergone primary percutaneous coronary intervention (PCI). Estimation of the success of reperfusion by the TIMI flow together with echocardiographic assessment and calculation of wall motion score index was performed in the 1st day and 3rd month of admission. Results: Patients with insufficient final coronary flow had highly significant elevated N/L ratios (11.9619±1.1864 vs. 4.9835±0.70985, P=0.000) and decreased lymphocyte count (952.92±309.284 vs. 1390.27±343.583, P=0.000). Conclusion: Higher N/L ratio should be considered as new lab marker for predicting both the lower rate of complete revascularization (TIMI 0, TIMI 1) and the higher incidence of complications after primary percutaneous coronary intervention.