PROTECTVE EFFICACY OF GINGER AGAINST ARSENIC INDUCED HEPATOTOXICITY IN SWISS ALBINO MICE
- Department of Zoology and Environmental Sciences, Punjabi University, Patiala-147002, Punjab, India.
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Arsenic is an ubiquitous element in the environment and it causes potential threat to human as well as animal health due to its carcinogenic activities. The present study was conducted to evaluate the protective role of ginger against arsenic induced hepatotoxicity in albino mice. Albino mice were divided into three groups. Group I were control mice, group II received an acute dose of arsenic (5 mg/kg bw) orally, group III received an acute dose of arsenic followed by daily administration of ginger (20mg/kg bw) orally. Autopsies were done on 15 days post treatment. Arsenic treatment leads to increase in weight of liver. Biochemical analysis of treated group showed decrease in antioxidant enzymes i.e. SOD and CAT but increased MDA content in liver as compared to control group. Ginger administration to mice decreased the weight of mice and showed significant protection in the alleviation of arsenic induced liver injury.
[Suman Sharma and Anjali Singh Gill (2015); PROTECTVE EFFICACY OF GINGER AGAINST ARSENIC INDUCED HEPATOTOXICITY IN SWISS ALBINO MICE Int. J. of Adv. Res. 3 (Oct). 580-585] (ISSN 2320-5407). www.journalijar.com
