Hypolipidamic studies on Egyptian propolis and Foeniculum Vulgare on alloxan induced diabetic rats

This study was carried out to evaluate the effect of Egyptian propolis and Foeniculum Vulgare on hypolipidamic in diabetic rats. Materials and methods: Diabetes was induced with Alloxan (148mg/Kg) intraperitoneal. Rats with blood glucose level less than 300 mg/dL were excluded. Animals were divided into 8 equal groups (n=80); except negative control rats, all groups inoculated with alloxan Group 1: negative control of normal rats. Group 2: positive control of alloxan injected rats. Group 3: rats were treated with 200 mg/ kg of propolis. Group 4: rats were treated with 400 mg/ kg of propolis. Group 5: rats were treated with 200 mg/ kg of Foeniculum vulgare. Group 6: rats were treated with 400 mg/ kg of Foeniculum vulgare. Group 7: rats were treated with (200 mg/ kg of Foeniculum vulgare+200 mg/ kg of propolis). Group 8: rats were treated with (400 mg/ kg of Foeniculum vulgare+400 mg/ kg of propolis). Rats were treated orally for 28 days. Results: Data showed significant increase in serum levels of Cholesterol, LDL, VLDL and triglyceride and significant decreased levels of HDL were observed in the diabetic untreated animals. Conclusion: Propolis and Foeniculum Vulgare possesses hypolipidamic activities.