Non Vascularized Autogenous Bone Grafts for Immediate Reconstruction of Segmental Mandibular Defects: a systematic Review

This systematic review was performed to address the focus question " what is the various success rates, difficulties and complications of non vascularised bone grafts for immediate segmental mandibular reconstruction" ,in addition, this article reviews recent advances ,different techniques, and possible complications of autogenous non vascularised bone grafts for mandibular reconstruction that were previously discussed in the literature. A thorough Medline database search performed on related terms yielded 14016. out of 398 abstracts selected, 124 full text articles were obtained for further evaluation. Results showed that a total of 18 studies followed the inclusion criteria. A primary analysis of the included studies showed that the majority were case series studies ( 11 articles) and only 3 Randomized controlled trials and 4 case reports were identified with most not providing objective and numerical outcomes of their results, Therefore quantitative data analysis and subsequent meta-analysis could not be performed. Results also showed variable success rates and complications of different immediate non vascularised autougenous graft forms. Many factors such as the size and site of the defect and the timing of reconstruction govern the success of the non vascularised bone grafts as an important option for immediate segmental mandibular reconstruction.