Isolation and Identification of Flavonoids from Heartwood of Acacia nilotica var nilotica and their Antibacterial Activity.
- Sudan University of Science and Technology, Faculty of Science.
- Gazira University, Faculty of Education.
- University of Bahri, College of Applied Sciences.
- Phytochemistry Department, National Research Centre, Cairo, Egypt.
- Department of Genetic Engineering , National Research Center Cairo, Egypt.
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From the methanolic extract of the heartwood of Acacia nilotica var nilotica, two compounds (I and II) were isolated ; compound I : 7, 3`, 4`-trihydroxy-3-methoxyflavone and compound II : 7, 3`, 4`-trihydroxyflavonol. The compounds were purified by different chromatographic techniques and identified via spectroscopic tools: IR, UV, 1HNMR and Mass spectroscopy.The isolated compounds were evaluated for their antimicrobial potential against Gram negative (Escherichia coli and Pseudomonas aeruginos) and Gram positive (Bacillus subtilis, Bacillus cereus and Staphylococcus aureus) bacteria. Both compounds showed varying antibacterial activity.
[M. Karim, A. M. Alraih, Inas O.K., M.A Alansari, and M. E.Moharan. (2016); Isolation and Identification of Flavonoids from Heartwood of Acacia nilotica var nilotica and their Antibacterial Activity. Int. J. of Adv. Res. 4 (Apr). 728-736] (ISSN 2320-5407). www.journalijar.com