PROTEOMICS: AN INSIGHT IN MOLECULAR DIAGNOSIS
- M.D.S, Senior Lecturer, Department of Oral and Maxillofacial Pathology and Microbiology, I.T.S Dental College, Hospital and Research Centre, Greater Noida, Uttar Pradesh, India.
- M.D.S, Senior Lecturer, Department of Periodontics and Oral Implantology, I.T.S Centre for Dental Studies and Research, Ghaziabad, Uttar Pradesh, India.
- M.D.S, Private Practitioner, Dr. Gautam’s Multispeciality Dental Clinic, Sigra, Varanasi, Uttar Pradesh, India.
- MDS Assistant Professor, Department of Prosthodontics, Dr M.C. Saxena College of Medical Sciences, Department of Dentistry, Dubagga IIM Bypass, Lucknow, Uttar Pradesh, India.
- M.D.S, Senior Lecturer, Department of Orthodontics and Dentofacial Orthopedics, Inderprastha Dental College, Ghaziabad, Uttar Pradesh, India.
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Proteins are the integral components of the physiological metabolic pathways of cells. Periodontitis is the result of complex interrelationship between infectious agents and host factors. The onset, progression and severity of periodontal disease are mainly mediated by various protein molecules. The proteome map, that is, complete catalogue of the matrix and cellular proteins expressed in alveolar bone, cementum, periodontal ligament, and gingiva, is to be explored for more in-depth understanding of periodontium. The knowledge of various proteins involved in periodontal disease pathogenesis can be used in the diagnosis, prevention and treatment of periodontal diseases.
[Amit Gupta, Swyeta Jain Gupta, Vivek Gautam, Tanmay Srivastava, Sidhant Taneja (2016); PROTEOMICS: AN INSIGHT IN MOLECULAR DIAGNOSIS Int. J. of Adv. Res. 4 (Nov). 2169-2173] (ISSN 2320-5407). www.journalijar.com
