HISTOPATHOLOGICAL STUDIES ON CARP (CYPRINUS CARPIO) EXPOSED TO FENTHION

Indian carp (Cyprinus carpio) were exposed to Fenthion (0.387, 0.193, 0.096 mg/l) for the period of 60 days. Fishes were sacrificed at the end of the trial period to study light micrscopic changes associated with toxicity. Liver, kidney, gill, and intestine were examined for histopathological studies. Swelling of the hepatocytes with diffuse necrosis and marked swelling of blood vessels were observed in the liver tissue. Tubules of the kidney were distended, with tubular cells of posterior kidney exhibited marked necrotic changes. Gill tissue showed fusion of primary lamellae, congestion of blood vessels and hyperplasia of branchial plates. After the exposure of Fenthion the secondary lamellae of the gills were shortened, deformed, swollen, ruptured and hyperplasia was observed. Many intestinal villi were ruptured near the tips; cellular exudates were also observed. Enlarged mucous cells filled with secretary materials were observed. Proliferations of mucous epithelial cells with pycnotic nuclei were seen.