Evaluation of candidial vaginitis treatment using different regiment of fluconazole

For any physician involved in the health care of women, the treatment of vaginitis remains a challenge. Vaginitis accounts for more than an estimated 10 million physician office visits annually, and it remains the most common reason for patient visits to obstetrician- gynecologists. Treatment of vaginitis has been undertaken and new approaches to the problem have been investigated. The purpose of this study was evaluation of different treatment protocol of fluconazole in women having candidial vaginitis. Evaluation and comparison of candidial vaginitis treatment with 150 mg single dose of Fluconazole versus 50 mg for 10 days of fluconazole in women in age of 15 to 45 year carried out in Boo- Ali Hospital. Current interventional experimental survey has performed as randomized clinical among patients attending to Boo-Ali Hospital during November 2011 to July of 2012. Patients received either 150 mg single dose of fluconazole or 50 mg for 10 days. Mean age of 125 women in this study was 33.4?7.9 year and 96.8% were married. 65 patients (52%) received single dose and 60 patients (48%) received 10 days regimen of fluconazole. 50% in single dose group and 67.7% in 10 days group had complete cure; but no statistically significant difference observed among two groups. In follow up of the next month, 10% of patients in the 10 days group and 25% in the single dose group had recurrence. It can be concludes that 10 days regimen has better therapeutic efficacy with lower recurrence rate compare to single dose of fluconazole.