MOLECULAR CHARACTERIZATION OF CHIKUNGUNYA AND DENGUE VIRUS AND THEIR ASSOCIATION WITH LIVER AND RENAL PROFILES

Dengue is a mosquito borne arbovirus infection endemic to most tropical and subtropical countries (1). Elevation of liver enzymes Aspartate Transaminase (AST) and Alanine Transaminase (ALT) is common in acute Dengue illness occurring in 65-97% (2345) of Dengue patients peaking during the convalescent period of illness (days7-10) (246). In Dengue endemic countries Dengue fever (DF) is important cause of the acute viral hepatitis (7). Dengue fever represents a severe flu like symptomatology which includes severe headache (retro-orbital) nausea vomiting muscle and joint pain (bone-break fever) and skin rash. According to WHO the incidence of DF has increased 30 folds ov...