EVALUATION OF COGNITIVE FUNCTIONS IN CHRONIC HCV ELDERLY PATIENTS.
- Professor of Internal Medicine, Geriatric Department, Faculty of Medicine, Alexandria University, Alexandria, Egypt.
- Assistant Professor of Internal Medicine, Hepatobiliary Department, Faculty of Medicine, Alexandria University, Alexandria, Egypt.
- Assistant Professor of Neuropsychiatry, Neuropsychiatry Department, Faculty of Medicine, Alexandria University, Alexandria, Egypt.
- Specialist of internal Medicine, Alexandria Fever Hospital, Alexandria, Egypt.
- Abstract
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Cognitive impairment is a decline in thinking, knowing, remembering, judging, problem solving, imagination, perception, and planning. Hepatitis C Virus (HCV) is a neurovirulent virus which induces cognitive dysfunction both directly and indirectly. The present study aimed to evaluate cognitive functions in elderly patients with chronic HCV infection. All subjects included in the study underwent neuropsychological assessment using Mini Mental State Examination (MMSE), Wechsler Intelligence Adult Scale (WIAS) tests, Hamilton Depression Rating Scale (HAM-D) and Hamilton Anxiety Rating Scale (HAM-A). An evident low score was reported among HCV elderly patients regarding MMSE and WIAS tests in comparison to normal control subjects. On the other hand, an evident high score was reported among HCV elderly patients regarding HAM-D and HAM-A tests in comparison to normal control subjects. HCV patients showed significant cognitive impairment with psychiatric disorders including depression and anxiety in comparison to normal control subjects.
[Sekina Ismail Ahmed, Perihan El Sayed Salem, Soha Abd Elatif Ahmed and Sara Taha Abd Elfatah. (2016); EVALUATION OF COGNITIVE FUNCTIONS IN CHRONIC HCV ELDERLY PATIENTS. Int. J. of Adv. Res. 4 (Dec). 2630-2637] (ISSN 2320-5407). www.journalijar.com
