20Jan 2017

IDENTIFYING EPIGENETIC ENDPOINTS OF PESTICIDE EXPOSURE CAN CURTAIL RISK TO DEVELOP CANCER: A REVIEW.

  • Department of Molecular and Human Genetics, Institute of Science, Banaras Hindu University, Varanasi, India.
  • Department of Zoology, Institute of Science, Banaras Hindu University, Varanasi, India.
  • Department of Zoology, Delhi University, New Delhi, India.
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Potential for carcinogenicity of pesticides is identified on the basis of its potential for causing genotoxicity. But, there are some pesticides that do not cause mutation at very early stage of exposure but result in silencing certain genes which make the cells addicted to oncogenic products to become neoplastic. This review throws light on the epigenetic changes brought about by pesticides, which effect the expression of genes without change in their DNA sequence. If certain epigenetics based tests are included in the panel of screening pesticides before they are introduced into the market, then not only will it help in deciding norms for regulating exposure to these chemicals but will also solidify our knowledge for that pesticide.

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[Rituparna Das, Kulbhushan Thakur, Anju Shrivastava, Akshita Puri and Mousumi Mutsuddi. (2017); IDENTIFYING EPIGENETIC ENDPOINTS OF PESTICIDE EXPOSURE CAN CURTAIL RISK TO DEVELOP CANCER: A REVIEW. Int. J. of Adv. Res. 5 (Jan). 1093-1107] (ISSN 2320-5407). www.journalijar.com

Rituparna Das
Department of Molecular and Human Genetics, Institute of Science, Banaras Hindu University, Varanasi, India

DOI:

Article DOI: 10.21474/IJAR01/2857      
DOI URL: http://dx.doi.org/10.21474/IJAR01/2857

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