27Mar 2017

PRENATAL DIAGNOSIS WITH GENETIC COUNSELING IN UHC SPLIT, CROATIA.

  • Gynecology and Obstetrics Outpetient Clinic, Split, Croatia.
  • Department for Medical Genetics with Laboratory for Human Genetics and Genetic Counseling Unit, Paediatrics Clinic, University Hospital Centre Split, Croatia.
  • School of Medicine, University of Split, Split, Croatia.
  • Gynecology and Obstetrics Clinics, University Hospital Centre Split, University of Split, School of Medicine, Split, Croatia.
  • Cytogenetic Laboratory, Paediatrics Clinic, Clinical Hospital Centre Zagreb, Croatia.
  • Institute Ru?er Boškovi?, Division of Molecular Medicine, Zagreb, Croatia.
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Abstract Purpose: The purpose of this study was to document the cytogenetic data obtained from amniotic fluid analysis, as a part of prenatal diagnosing. Methods: 1.441 samples were analyzed by standard cytogenetic method. Results: Indications for amniocentesis were divided into six groups. Of them advanced maternal age was the most common, and, as expected, it was associated with the largest number of pathological cytogenetic findings. Conclusion: In comparison to other indicators for amniocentesis, advanced maternal age had a highest positive predictive value. Key words: prenatal diagnosing, genetic counseling, cytogenetic analysis, amniocentesis


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[Robert Vulic, Vida Culic, Silvana Miskovic, Ivana Gunjaca, Damir Roje, Ruzica Lasan and Jasminka Pavelic. (2017); PRENATAL DIAGNOSIS WITH GENETIC COUNSELING IN UHC SPLIT, CROATIA. Int. J. of Adv. Res. 5 (3). 1272-1276] (ISSN 2320-5407). www.journalijar.com


Vida ?uli?
Paediatrics, genetics, genetic counseling, cytogenetics

DOI:


Article DOI: 10.21474/IJAR01/3632       DOI URL: http://dx.doi.org/10.21474/IJAR01/3632


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