31May 2017

TO DETERMINE THE LEVELS OF FREE-FATTY ACID, LIPID-PEROXIDATION AND THE ROLE OF NON- ENZYMATIC ANTIOXIDANT IN PRE-ECLAMPSIA COMPARED WITH NORMAL PREGNANCY.

  • Assistant Professor, Department of Biochemistry MLN Medical College, Allahabad.
  • Associate Professor, Department of Obs & Gynae, MLN Medical College, Allahaba.
  • Demonstrator, Department of Biochemistry, MLN Medical College, Allahabad.
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Preeclampsia is a hypertensive disorder and is one of the most leading causes for maternal and fetal mortality in developing countries. The aim of the present study was to determine the relationship of serum levels of free fatty acid, non-enzymatic antioxidant (Vit E& Vit C) and lipid-peroxidation assessed by levels of malondialdehyde in preeclampsia. The study population consisted of 100 pre-eclamptic patients and 100 matched healthy pregnant women. Serum levels of free fatty acid assessed using commercially available Kit assay methods. The amount of malondialdehyde was determined by the thiobarbituric acid assay, Vitamin E and Vitamin C by Emer Engel and Carl A Burtis Method. Statistical analysis was performed using the student t test analysis. Serum levels of malondialdehyde were significantly increased in preeclamptic group compared with normal pregnant women. Higher level of lipid-peroxidation in serum is a marker of oxidative stress which play important role in the etiopathaogenesis of preeclampsia in pregnancy.

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[Shweta Dwivedi, Urvashi Singh and Afreen Arsad Chowdhary. (2017); TO DETERMINE THE LEVELS OF FREE-FATTY ACID, LIPID-PEROXIDATION AND THE ROLE OF NON- ENZYMATIC ANTIOXIDANT IN PRE-ECLAMPSIA COMPARED WITH NORMAL PREGNANCY. Int. J. of Adv. Res. 5 (May). 2254-2257] (ISSN 2320-5407). www.journalijar.com

Dr. Shweta Dwivedi
MLN Medical College Allahabad

DOI:

Article DOI: 10.21474/IJAR01/4373      
DOI URL: http://dx.doi.org/10.21474/IJAR01/4373

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