28Jul 2017

BEHAVIORAL CHANGES INDUCED BY TOXOPLASMOSIS IN ANIMALS AND HUMANS.

  • Centro de Pesquisas em Sanidade Animal, FCAV/UNESP, Jaboticabal, SP.
  • Departamento de Apoio, Produ??o e Sa?de Animal, FMV/UNESP, Ara?atuba, SP.
  • Empresa Brasileira de Pesquisa Agropecu?ria, EMBRAPA Su?nos e Aves, Conc?rdia, SC.
  • Departamento de Cl?nica e Cirurgia Veterin?ria, FCAV/UNESP, Jaboticabal, SP.
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In this literature review, we compiled information on the behavioral changes induced by toxoplasmosis in animals and humans. Pathologies due to toxoplasmic infection have been widely studied, but the chronic effects and modulation of the parasite-host interaction remain uncertain. In experimental infections of small rodents, behavioral changes have been investigated mainly through leakage parameters, assessment of motor sensory cognitive functions, as well as dopamine activity and release. Chimpanzees also showed behavioral changes, a phenomenon characterized, even, by specific aversion to their only predators. In adult humans, it has been proposed that tissue cysts exert behavioral changes in their hosts, either directly or through the release of metabolic products. Thus, chronic infection with Toxoplasma gondii has been associated with reduced motor reflex, increasing the risk of traffic accidents, as well as the inversion in personality, resulting in a lower score in the intelligence quotient (IQ), reduction in attainment Higher stages of schooling and, in the elderly, impairment of memory. Finally, it has been considered the hypothesis that dopamine may be involved in this process, since the psychomotor performance is lower in the infected individuals, still related chronic infection to Obsessive Compulsive Disorder, Parkinson's disease, suicide attempts, Autism, schizophrenia, Bipolar and Anxiety Disorders. Therefore, in this analysis, we demonstrate reports of scientific evidence of behavioral changes induced by both animal and human toxoplasmosis.

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[Murilo Abud Bichuette, Alvimar Jos? da Costa, Ane Pamela Capucci Torres, Gl?ucio Lu?s Mata Mattos, Guadalupe Sampaio Ferreira, Lucas Vin?cius Costa Gomes, Willian Marinho Dourado Coelho and Katia Denise Saraiva Bresciani. (2017); BEHAVIORAL CHANGES INDUCED BY TOXOPLASMOSIS IN ANIMALS AND HUMANS. Int. J. of Adv. Res. 5 (Jul). 2009-2014] (ISSN 2320-5407). www.journalijar.com

Murilo Abud Bichuette
UNESP - São Paulo State University, Jaboticabal, São Paulo, Brazil

DOI:

Article DOI: 10.21474/IJAR01/4936      
DOI URL: http://dx.doi.org/10.21474/IJAR01/4936

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