SERUM LIPID LEVELS, AND RELATION OF STROKE WITH DIFFERENT COMPONENTS OF SERUM LIPIDS IN PATIENTS WITH STROKE.

Background: A stroke occurs when a blood vessel that carries oxygen and nutrients to the brain either bursts, ruptures or is blocked by a clot. As a result, the brain cannot get the blood and oxygen it needs and pieces of the brain die. Stroke Risk Factors though some stroke risk factors are uncontrollable, such as age and race, other risk factors are controllable For example, hypertension, smoking. This case-control study Focus on the role lipid wich involved serum cholesterol ,serum triglyceride ,serum hight density lipoprotein ,serum low density lipoprotein Aims and objectives: 1. To know several reasons and risk factors lead to developing trokes. 2.Are lipid profile changes thought to be a risk factor in theoccurrence of stroke. Patients and methods: This study is a cross sectional study conducted in the Neurology department of Rhizgary teaching hospital in Erbil city in Iraqi Kurdistan from November 2015- September, 2016 comprised 90 patients (50) males and (40) females were diagnosed on the basis of clinical to have strock to see the relation different components of serum lipids and ischemic stroke. Healthy control (HC) group: fourty healthy individuals comprised of 10 males and 30 females (mean age of total 40 healthy control was 35.5?5.6 years) had been chosen from hospital medical staff, who have no history or clinical evidence of stroke or any chronic disease, they were age and sex matched their ages ranged from 27 to 55 years. Result: Result showed that ischemic stroke was more common after the age of 50 years with mean age of (56.428? 12.499) years. Male suffered more than female from ischemic stroke (M:F=3:1). Hypertension and diabetes mellitus (DM) were found to be highly significant risk factors for ischemic stroke (P<0.01). High level of both serum triglyceride ,low density lipoprotein (LDL) showed highly significant (p<0.01). Inaddition, low level of high density lipoprotein (HDL) appeared as a highly significant risk factor (p<0.01) In contrast to cholesterol level on showed no significant effect on ischemic stroke (p>0.05). Conclusions: We could be concluded that TG,HDL LDL, cholesterol levels can be considered as a risk factor for both ischemic cerebral and stroke events. The main risk factor for stroke is high blood pressure. In addition, diabetes mellitus.