29Oct 2017


  • Biology Department, College of Science / Majmaah University, K.S.A.
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Background: Toxic heavy metals in water, air and soil are global problems that are a growing threat to humanity. Heavy metals are widely distributed in the environment and some of them occur in food, water, air and tissues even in the absence of occupational exposure. Aim: To investigate the antioxidant and protective influences of vitamin E and/or zinc on some heavy metals (lead, cadmium and mercury) induced oxidative stress and testicular injuries in male rats. Results: Results showed that exposure to lead, cadmium or/and mercury causes damage or alterations in the testicular functions in male albino rats. On the other hand, vitamin E or/and zinc administration lessened or cured these damages and repaired the destruction which occurred because of exposure to these toxic substances. Conclusion: heavy metals stimulated different hazardous effects leading to testicular dysfunction in male rats, and the supplementation of vitamin E or/and zinc play(s) an important role to minimize and reduce the harmful effects of heavy metal exposure. These improvements are attributed to the antioxidant functions of vitamin E and zinc. In addition, suggestions for further studies were recommended.

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Marwan Abdel-Latif Ibrahim
Assistant Professor of Applied Physiology Department of Biology Faculty of science Majmaah University


Article DOI: 10.21474/IJAR01/5709      
DOI URL: http://dx.doi.org/10.21474/IJAR01/5709