- Cite This Article as
- Corresponding Author
The present study was carried out to analyse the culture reports 470 urine samples collected from symptomatic patients between 18 to 80 years from department of medicine, surgery and gynaecology from May 2017 to 0ctober 2017. All the samples collected during the above period were subjected for culture sensitivity as per standard methods. The most common infection encountered in clinical practice is urinary tract infection. Urinary tract infection can be caused by different microorganisms including bacteria, parasites, fungi and viruses which are the major causative organisms. Among these, bacteria account for more than 95% of Urinary tract infection cases. Escherichia coli is the commonest urinary pathogen accounting for over 80% of community acquired infection. In this study the most common pathogenic organism isolated was Escherichia coli 44(55.69%) followed by Staphylococcus aureus 20(25.31%) and Klebsiella species 11(13.92%) in both males and females. Escherichia coli were sensitive to nitrofurantoin, amikacin and piperacillin tazobactam in 35 (79.4%), 25(56.81%) and 18(40.95%) respectively. Similarly 16(80%) of Staphylococcal isolates were sensitive to nitrofurantoin 11(55%) to amikacin and 5(25%) to piperacillin tazobactam. Klebsiella isolates also showed highest sensitivity to nitrofurantoin and piperacillin tazobactam 7(63%) followed by ceftriaxone 6 ( 54%.) This study will help clinicians to choose the right empirical antibiotics, and they should take into account the local sensitivity and resistance patterns while prescribing empirical oral or intravenous antibiotics.
- Akram M, Shahid M and Khan AU (2007). Etiology and antibiotic resistance patterns of community acquired urinary tract infections in J N M C Hospital Aligarh, India. Annals of Clinical Microbiology and Antimicrobials 6 4
- Amarjit singh vij, Shashi chopra and Jigyasa sehgal. Two years retrospective study of antibiotic resistance pattern of uropathogens especially Escherichia coli in north India. Cibtech journal of microbiology. 2014 vol. 3 (2) April-June, pp. 29-36.
- Ana L.Flores-Mireles, Jennifer N.Walker, Michael Caparon and Scott J.Hultgren nary tract infections: Epidemiology, mechanisms of infection and treatment options. Nature Reviews Microbiology13(5)???April 2015
- Angus N. Oli et al. Bacteriology and Antibiogram of Urinary Tract Infection Among Female Patients in a Tertiary Health Facility in South Eastern Nigeria The Open Microbiology Journal, 2017, Volume 11 293
- Avinash Laghawe, Apoorva Tripathi and S B Saxena. Aetiology of Urinary Tract Infection and antimicrobial susceptibility pattern of urinary isolates in tertiary care hospital in Central India: A retrospective analysis. J.Curr.Microbiol.App.Sci (2015) 4(4): 962-970.
- Banerjee S and Padmashri VP (2011). The Study of Urinay Tract Infections and Antibiogram of Uropathogens in and around Ahmadnagar, Maharashtra. International Journal of Infectious Diseases 9(1)
- Bauer AW, Kirby WM, Sherris JC and Turck M (1966). Antibiotic susceptibility testing by a standardized single disk method. American Journal of Clinical Pathololgy 45 493‑6.
- CLSI?Clinical and Laboratory Standards Institute 2016. Performance standards for antimicrobial susceptibility testing. Twenty-second informational supplement. Wayne, PA, USA.
- Dash M, Padhi S, Mohanty I, Panda P and Parida B (2013). Antimicrobial resistance in pathogens causing urinary tract infections in a rural community of Odisha, India. Journal of Family & Community Medicine 20 20-6.
- Florian M. E. Wagenlehner, Udo Hoyme, Martin Kaase, Reinhard F?nfst?ck, Kurt G. Naber, Guido Schmiemann Dtsch Arztebl. Uncomplicated Urinary Tract Infections. Int 2011; 108(24): 415?23
- Kothari A and Sagar V (2008). Antibiotic resistance in pathogens causing community acquired urinary tract infections in India: a multicenter study. Journal of Infection in Developing Countries 2(5) 354-358
- Kumar Y, Sood S, Sharma A and Mani KR (2013). Antibiogram and characterization of resistance markers among Escherichia coli isolates from urinary tract infections. Journal of Infection in Developing Countries 7(7) 513-9.
- LE Nicolle. Complicated urinary tract infection in adults. Can J Infect Dis. Med Microbiol 2005; 16(6 349-360.
- Mohamoud d Dobabash et al. Antibiogram Sensitivity in Urinary Tract Infections (UTI) at El Batnan Medical Center- Tobruk ? Libya. Urol Nephrol Open Access J 2017, 4(3): 1.
- Monika Yadav et al Microbial spectrum of urinary tract infections and its antibiogram in a tertiary care hospital Int J Res Med Sci. 2017 Jun;5(6):2718-2722
- Mulugeta Kibret, Bayeh Abera. Prevalence and antibiogram of bacterial isolates from urinary tract infections at Dessie Health Research Laboratory, Ethiopia Asian Pac J Trop Biomed 2014; 4(2): 164-168
- Nasim Kashef, Gholamreza Esmaeeli Djavid, Sahba Shahbazi. Antimicrobial susceptibility patterns of community-acquired uropathogens in Tehran, Iran. J Infect Dev Ctries 2010; 2010; 4(4):202-206
- Niranjan V, Malini A. Antimicrobial resistance pattern in Escherichia coli causing urinary tract infection among inpatients. Indian J Med Res. 2014;139(6):945.
- Venkatesh Naik, Basavaraj V. Peerapur . A Retrospective Study of the Culture and Sensitivity Pattern of Urinary Tract Infection Causing Organisms at RIMS Teaching Hospital, Raichur, India. Int.J.Curr.Microbiol.App.Sci (2017) 6(10): 1530-1536.
- Rajesh KR, Mathavi S, Priyadarsini RI. Prevalence of antimicrobial resistance in uropathogens and determining empirical therapy for urinary tract infections. International Journal. 2010 Oct;1(5):260.
- Sood S and Gupta R (2012). Antibiotic Resistance Pattern of Community Acquired Uropathogens at a Tertiary Care Hospital in Jaipur, Rajasthan. Indian Journal of Community Medicine 37 39-44.
- Swati Talari, Padmaja Udaykumar. A Retrospective Study to Assess the Resistance Profile Among Pathogens Causing Urinary Tract Infection In Pediatric Population At A Tertiary Hospital. Journal of Pharmacy and Biological Sciences: Volume 12, Issue 3 Ver. V (May ? June 2017), PP 32-36.
[Swathi Kuna, P. Ratna Kumari and R.Lakshmi Kumari. (2019); STUDY OF URINARY TRACT INFECTIONS IN TERTIARY CARE HOSPITAL EMPHASIZING ON BACTERIOLOGICAL PROFILE WITH ANTIBIOGRAM. Int. J. of Adv. Res. 7 (2). 158-162] (ISSN 2320-5407). www.journalijar.com
M.D., Professor, Department of Microbiology ,Siddhartha Medical College,Vijayawada-520008
Article DOI: 10.21474/IJAR01/8472 DOI URL: http://dx.doi.org/10.21474/IJAR01/8472
Share this article
This work is licensed under a Creative Commons Attribution 4.0 International License.