15Nov 2019

EARLY DETECTION OF ALZHEIMERS DISEASE USING MACHINE LEARNING TECHNIQUES

  • Department of Electronics and Communication Engineering, Faculty of Computer Science and Engineering, Hajee Mohammad Danesh Science & Technology University, Dinajpur, Bangladesh
  • Abstract
  • Keywords
  • References
  • Cite This Article as
  • Corresponding Author

Alzheimers Disease (AD) is believed to be the most widely recognized reason for dementia and it is assessed that lone 1-in-4 individuals with Alzheimers are accurately diagnosed in an opportune manner. While no authoritative fix is accessible, when the weakness is still mellow the side effects can be overseen and treatment is best when it is begun before critical downstream harm happens, i.e., at the phase of mild cognitive impairment (MCI) or considerably prior. AD is clinically analyzed by physical and neurological assessment, and through neuropsychological and intellectual tests. There is a need to grow better diagnostic tools, which is the thing that this postulation addresses. OASIS is an open access dataset accessible online for improving the determination strategy of Alzheimers malady. Information gathered at meeting is recorded and one point of the work in this theory is to investigate the utilization of machine learning strategies to produce a classifier that can help with screening new people for various phases of AD. Contrasted with the past work processes, our technique is fit for breaking down different classes in a single setting and requires less marked training samples and insignificant domain earlier information. A notable performance gain on classification of all diagnosis groups was accomplished in our examinations. The model is prepared at first on 416 analyzed cases got from OASIS database. We at that point test our prepared model on the whole arrangement of entries provided by OASIS dataset to affirm the accuracy of discovery by our framework. Our outcomes produce 94.37% exactness in AD detection and classification


  1. Dubois, B., Feldman, H. H., Jacova, C., Hampel, H., Molinuevo, J. L., Blennow, K., ... & Cappa, S. (2014). Advancing research diagnostic criteria for Alzheimers disease: the IWG-2 criteria.?The Lancet Neurology,?13(6), 614-629.
  2. Farouk, Y., Rady, S., & Faheem, H. (2018, April). Statistical features and voxel-based morphometry for alzheimers disease classification. In?2018 9th International Conference on Information and Communication Systems (ICICS)(pp. 133-138). IEEE.
  3. ADNI?|?Alzheimers Disease Neuroimaging Initiative. Retrieved 10 May 2019, from http://adni.loni.usc.edu/
  4. Khajehnejad, M., Saatlou, F., & Mohammadzade, H. (2017). Alzheimers disease early diagnosis using manifold-based semi-supervised learning.?Brain sciences,?7(8), 109.
  5. OASIS Brains - Open Access Series of Imaging Studies. Retrieved 14 May 2019, from https://www.oasis-brains.org/
  6. Hosseini-Asl, E., Keynton, R., & El-Baz, A. (2016, September). Alzheimers disease diagnostics by adaptation of 3D convolutional network. In?2016 IEEE International Conference on Image Processing (ICIP)(pp. 126-130). IEEE.
  7. Moradi, E., Pepe, A., Gaser, C., Huttunen, H., Tohka, J., & Alzheimers Disease Neuroimaging Initiative. (2015). Machine learning framework for early MRI-based Alzheimers conversion prediction in MCI subjects.?Neuroimage,?104, 398-412.
  8. Suk, H. I., Lee, S. W., Shen, D., & Alzheimers Disease Neuroimaging Initiative. (2014). Hierarchical feature representation and multimodal fusion with deep learning for AD/MCI diagnosis.?NeuroImage,?101, 569-582.
  9. Savio, A., Grańa, M., & Villan?a, J. (2011, May). Deformation based features for Alzheimers disease detection with linear SVM. In?International Conference on Hybrid Artificial Intelligence Systems(pp. 336-343). Springer, Berlin, Heidelberg.
  10. Hollingshead, A. D. B. (1975). Four factor index of social status.
  11. Scikit-learn: machine learning in Python ? scikit-learn 0.20.3 documentation. Retrieved from http://scikit-learn.org/stable/
  12. Machine Learning, Data Science, Big Data, Analytics, AI. Retrieved from https://www.kdnuggets.com/
  13. NumPy ? NumPy. Retrieved from https://numpy.org/
  14. org ? SciPy.org. Retrieved from https://www.scipy.org/
  15. Matplotlib: Python plotting ? Matplotlib 3.1.1 documentation. Retrieved from https://matplotlib.org/

[Ariful Islam Khan, Saiful Islam, Sanjida Tasnim Shorno, Sumonto Sarker and Abubakar Siddik (2019); EARLY DETECTION OF ALZHEIMERS DISEASE USING MACHINE LEARNING TECHNIQUES Int. J. of Adv. Res. 7 (11). 235-242] (ISSN 2320-5407). www.journalijar.com


Md. Ariful Islam Khan
Hajee Mohammad Danesh Science & Technology University, Dinajpur, Bangladesh.

Share this article