AlternationofCCl4 -Induced Oxidative Stressand Nephrotoxicity by Omega-3 in Female Albino Rats.
- MSc. Biology, Physiology/ College of Science/ University of Salahaddin – Erbil.
- MSc. Histophysiology, Lecturer, Health prevention department/Medical Technical Institute/ University of polytechnic-Erbil, Iraq.
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Abstract
In the present study, twenty one female albino rats were used and they were divided in to three groups. This was carried out and designed to study the effect of omega 3 poly unsaturated fatty acid on carbon tetrachloride (CCl4) induced oxidative stress and kidney damage in female albino rats. However, the antioxidant activity of omega-3 were determined by assessing biochemical parameters (serum creatinine, urea, uric acid, and malondialdehyde(MDA)). Carbon tetrachloride caused significant increase inserumcreatinine, urea, uric acid, and MDA levelwhile, omega 3 significantly prevented the increase of the serum levels of creatinine, urea, uric acid, and MDA.
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Hawzheen K. Othman and Tahseen A. Abdullah. (2016); AlternationofCCl4 -Induced Oxidative Stressand Nephrotoxicity by Omega-3 in Female Albino Rats., International Journal of Advanced Research (IJAR), 4 (07), 1789-1795, ISSN 2320-5407. DOI: https://doi.org/10.21474/IJAR01/1001
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