Relationship between Myocardial Performance Index and Severity of Coronary Artery Disease in patients with Stable Coronary Artery Disease.

Background:- MPI showed the ability of being a sensitive marker of LV function in SCAD as its value was impaired in proportion to severity of coronary obstruction and it is correlated well with Syntax score as it is the most recent quantitative and qualitative tool that can characterizes angiographically obstructive lesions, risk stratification and prognostication of patients with CAD. Aim of the study:- The aim of the study was to investigate the relationship between severity of coronary artery disease (CAD) assessed with SYNTAX score (SS) and myocardial performance index (MPI) in stable CAD. Material and methods:- The study included 100 patients who were candidate for coronary angiography. All subjects underwent full history taking, complete clinical examination, echocardiographic examination for calculation of MPI, EF and E/A ratio, and coronary angiography for calculation of syntax score. Results:- Among study population 49 female (49.0%) and 51 male (51.0%) with mean age (48.96±7.30), 80 patients (80.0%) were had angiographically proven obstructive CAD, whereas 20 (20.0%) patients were had normal coronary angiography. There is statistically significant positive correlation between MPI and SS in patients with obstructive CAD (P-value < 0.001).