A REVIEW ON EFFECT OF CYSTATIN C IN TYPE 2 DIABETES MELLITUS.

Diabetes mellitus is a metabolic disorder resulting from deficient insulin secretion, inefficient insulin action or both leading to prolongedhyperglycemia. Diabetic problems result from the toxic effects of prolonged hyperglycemia combined with other metabolic imbalances. type 2 diabetes mellitus, formerly called non-insulin-dependent diabetes mellitus, is a serious, costly disease. Treatment prevents some of its devastating complications but does not usually restore normoglycemia or eliminate all the adverse consequence . Cystatin C is a cysteine protease inhibitor with a low-molecular weight that is produced by all nucleated cells at a constant rate. Cystatin C also produce contraindication like it play a major role in the thyroid functions, Kidney,CVS.