Synthesis of Schiff bases of N- based methylene derivatives

A simple and efficient method has been developed for the synthesis of some Schiff bases via the reaction of aromatic aldehydes with 44’-Methylenebis 2-methyl aniline by using catalytic amount of glacial acetic acid in an organic solvent at room temperature. Some advantages of this protocol are its very good yields, use of available catalysts, simple workup procedure, and short reaction times.