30Jan 2017

METHEMOGLOBINEMIA DUE TO BIOLOGICAL POISONING – CASE REPORT

  • Postgraduate,General Medicine, Dr.Pinnamaneni Siddhartha Institute of medical sciences and research foundation ,Chinaoutpalli, Krishna district, Andhra Pradesh.
  • AssociateProfessor, Dept. of General Medicine,Dr.Pinnamaneni Siddhartha Institute of medical sciences and research foundation, Chinaoutpalli, Krishna district, Andhra Pradesh, India.
  • Professor and HOD, Dept. of General Medicine, Dr.Pinnamaneni Siddhartha Institute of medical sciences and research foundation, Chinaoutpalli, Krishna district, Andhra Pradesh, India.
  • Abstract
  • Keywords
  • References
  • Cite This Article as
  • Corresponding Author

Acquired methemoglobinemia is a dyshaemoglobinemia which results from exposure to various oxidizing agents, results in impaired oxygen delivery to the tissues and can be potentially fatal if untreated. Deliberate ingestion of certain herbicides, insecticides, and pesticides may produce this condition. We report 2 cases of methemoglobinemia due to intentional ingestion of pesticides which were marketed to be safe and contain only biological extracts and fillers. Methylene blue, ascorbic acid, blood transfusion and exchange transfusion are the various modalities of treatment.


  1. Dewan A, Patel AB, Saiyed HN. Acute methemoglobinemia- A common occupational hazard in an industrial city in western India. Journal of Occupational Health. 2001; 43(3): 168-171.
  2. Donovan JW:Nitrates, nitrites and other sources of methemoglobinemia. In Clinical management of poisoning and drug overdose. Edited by Haddad LM, Winchester JF. W.B. Saunders Company, Philadelphia; 1990:1419-1431.
  3. Ash-Bernal R, Wise R, Wright SM. Acquired methemoglobinemia: a retrospective series of 138 cases at 2 teaching hospitals. 2004 Sep; 83(5):265-73.
  4. George T, Shaikh AI, Thomas L, Kundavaram AP.
  5. Severe methemoglobinemia due to insecticide poisoning. Indian J Crit Care Med 2014; 18:113-4
  6. Abu-Laban RB, Zed PJ, Purssell RA, Evans KG. Severe methemoglobinemia from topical anesthetic spray: Case report, discussion and qualitative systematic review. CJEM 2001; 3:51-6.
  7. Gharahbaghian L, Massoudian B, Dimassa G. Methemoglobinemia and sulfhemoglobinemia in two pediatric patients after ingestion of hydroxylamine sulfate. West J Emerg Med 2009; 10:197-201.
  8. Chongtham DS, Phurailatpam J, Singh MM, Singh TR: Methaemoglobinemia in nitrobenzene poisoning. J PostgradMed 1997, 43(3):73–
  9. Rees SM, Nelson LS: In Emergency medicine - a comprehensive study guide. 6th edition. Edited by Tintinalli JE, Kelen GD, Stapczynski JS. McGraw-Hill, New York; 2004:1169-1171.
  10. doNascimento TS, Pereira RO, de Mello HL, Costa J. Methemoglobinemia: From diagnosis to treatment. Rev Bras Anestesiol 2008; 58:651-64
  11. Perera M, Shihana F, Kularathne K, Dissanayake D, Dawson A. Acute methaemoglobinaemia after massive nitrobenzene ingestion, BMJ Case Rep 2009;2009.

[Geethika Sai Nutakki, Indraja Siripurapu, Ch. Manoj Kumar and T V D Sasi Sekhar. (2017); METHEMOGLOBINEMIA DUE TO BIOLOGICAL POISONING – CASE REPORT Int. J. of Adv. Res. 5 (Jan). 2079-2082] (ISSN 2320-5407). www.journalijar.com


DR.GEETHIKA SAI NUTAKKI
DOCTOR

DOI:


Article DOI: 10.21474/IJAR01/2980      
DOI URL: https://dx.doi.org/10.21474/IJAR01/2980