HYPOTHALAMIC CAVERNOMA IN A 28 YEARS OLD SAUDI LADY: CASE REPORT
- Assistant professor of neurology, Head of Internal Medicine Department, College of Medicine - Taif University, Saudi Arabia.
- Abstract
- Keywords
- References
- Cite This Article as
- Corresponding Author
Background:Cerebral vascular malformations occur in 0.1-4% of the general population.Cavernoma is a subtype of these malformations with 0.4% incidence rate.Symptoms vary from absence to various neurological sequelae.We believe it's important to report this case because it strongly emphasizes that patients should not be profiled, and chronic complaints may need reassessment. Case Presentation:We report a case of 28-years old Saudi ladywith cerebral cavernoma. She is complaining ofchronic headache for five years with recurrent attacks of severe headache for the last two years. Conclusion:Cavernoma is the least common vascular malformation in central nervous system which may cause serious complications.Decision about management depends on whether it is symptomatic or not.Hence,patients should be evaluated carefully and chronic complaints should always be revisited.
- Rigamonti D, Hardley MN, Drayer BP, et al.Cerebral cavernous malformations.Incidence and familial occurrence.NEngl J Med 1988;319:343.
- McCormick, WF. Pathology of vascular malformations of the brain. In: Intracranial Arteriovenous Malformations,Wilson, CB, Stein, BM(Eds), William&Wilkins,Baltimore, MD 1984. p.44.
- Russell, DS, Rubinstein, LJ. Pathology of Tumours of the Nervous System. 5th William&Wilkins,Baltimore, MD 1989. p.727.
- Dubovsky J, Zabramski JM, Kurth J, et al.A gene responsible for cavernous malformations of the brain maps to chromosome 79.Hum Mol Genet 1995; 4:453.
- Laberge-Le Couteulx S, Jung HH, Labauge P, et al.Truncating mutations in CCM1, encoding KRIT1, cause hereditary cavernous angiomas.Nat Genet 1999; 23:189.
- Verlaan DJ, Davenport WJ, Stefan H, et al.Cerebral cavernous malformations:mutations in Krit1.Neurology 2002; 58:853.
- Mc Cormick, PC, Michelson, WJ. Management of intracranial cavernous and venous malformations.In: Intracranial vascular malformations, Barrow, DL(Ed), American Association of Neurological Surgeons. Park Ridge, IL 1990.P.197.
- Tew, JM, Sathi, S. Cavernous Malformations.In: Primer on Cerebrovascular Diseases, Welch, KM, Caplan, LR, Reis, DJ, et al.(Eds), Academic Press. San Diego, CA 1997. P.550.
- Robinson JR, Awad IA, Little JR. Natural history of the cavernous angioma. J Neurosurg 1991; 75:709.
- Aiba T, Tanaka R, Koike T, et al. Natural history of intracranial cavernous malformations. J Neurosurg 1995; 83:56.
- Fritschi JA, Reulen HJ, Spetzler RF, Zabramski JM. Cavernous malformations of the brain stem. A review of 139 cases. ActaNeurochir(Wien)1994;130:35.
- Kondziolka D, Lunsford LD, Kestle JR. The natural history of cerebral cavernous malformations. J Neurosurg 1995;83:820.
- AL-Shahi Salman R, Hall JM, Home MA, et al. Untreated clinical course of cerebral cavernous malformations: a prospective,population-based cohort study. Lancet Neurol 2012;11:217.
- Flemming KD, Link MJ, Christianson TJ, Brown RD Jr. Prospective haemorrhage risk of intracerebral cavernous malformations. Neurology 2012;78:632.
- Robinson JR jr, Awad IA, Magdinec M, Paranandi L. Factors predisposing to clinical disability in patients with cavernous malformations of the brain. Neurosurgery 1993; 32:730.
- Rigamonti D, Hadley MN, Drayer BP, et al. Cerebral cavernous malformations. Incidence and familial occurrence. N Engl J Med 1988; 319:343.
- Kamezawa T, Hamada J, Niiro M, et al. Clinical implications of associated venous drainage in patients with cavernous malformations. J Neurosurg 2005; 102:24.
- Baumann CR, Acciarri N, Bertalanffy H, et al. Seizure outcome after resection of supratentorial cavernous malformations: a study of 168 patients. Epilepsia 2007; 48:559.
- Cohen DS, Zubay GP, Goodman RR. Seizure outcome after lesionectomy for cavernous malformations. J Neurosurg 1995; 83:237.
[Naif Edah Alomairi. (2017); HYPOTHALAMIC CAVERNOMA IN A 28 YEARS OLD SAUDI LADY: CASE REPORT Int. J. of Adv. Res. 5 (Jan). 2270-2274] (ISSN 2320-5407). www.journalijar.com
Internal Medicine Department, College of Medicine - Taif University