FEBRILE CONVULSIONS AND IRON DEFICIENCY ANEMIA: A CASE-CONTROL STUDY IN ZAGAZIG UNIVERSITY HOSPITALS, EGYPT.

  • Department of Neurology, Faculty of Medicine, Zagazig University.
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Background: Febrile convulsion (FC) is the most common convulsive disorder in children. The maximum age of occurrence is 14-18 months, which overlaps with the maximum prevalence of iron deficiency anemia (IDA) which is 1-2 years old. Aim: To compare the iron deficiency rates in children with febrile convulsions with those in the febrile children without convulsions. Subjects: This case-control study included 50 FC children (case group) with mean age of 30.319.2 months and 50 children with febrile illness without convulsion (control group) with mean age of 28.819.3 months attended to outpatient clinics of Neurology and Pediatric Departments, Zagazig University hospitals. Methods: All patients had detailed history taking, thorough clinical general and neurological examination, laboratory tests (complete blood count, hemoglobin level, hematocrit value, mean corpuscular volume, serum ferritin level, serum iron level, total iron-binding capacity), and EEG . Results: Respiratory tract infection & history of previous seizure were significantly higher in cases. Microcytosis & IDA were significantly more frequent in febrile seizure group. Median serum iron & mean serum ferritin levels were significantly lower in cases. Generalized seizures were significantly higher and the mean duration of seizures was significantly longer in cases with iron deficiency than in those without iron deficiency. Focal seizures were significantly more frequent in cases without iron deficiency. Conclusion: children with low serum iron level and those having iron deficiency anemia are more liable to develop FC when compared with those with febrile illness without convulsion.

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[Walid M. Reda Ashour, Hala A. Fathy, Tamer S. Elserafy and Wael Mahmoud. (2017); FEBRILE CONVULSIONS AND IRON DEFICIENCY ANEMIA: A CASE-CONTROL STUDY IN ZAGAZIG UNIVERSITY HOSPITALS, EGYPT. Int. J. of Adv. Res. 5 (Feb). 1781-1786] (ISSN 2320-5407). www.journalijar.com

Walid Reda Ashour
MD, Lecturer at Department of Neurology, Faculty of Medicine, Zagazig University, Egypt

DOI:

Article DOI: 10.21474/IJAR01/3341      
DOI URL: https://dx.doi.org/10.21474/IJAR01/3341

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