SERUM TOTAL CALCIUM, MAGNESIUM, SODIUM AND POTASSIUM IN SUDANESE WOMEN WITH PREECLAMPSIA.

Preeclampsia is characterized by new-onset hypertension, proteinuria and is responsible for substantial maternal and fetal morbidity. The electrolytes like sodium, potassium and chloride contribute significantly in the functioning of the vascular smooth muscles and may play an important role in hypertension. This study was carried out to measure serum levels of sodium, potassium, magnesium and calcium in preclamptic women. Sixty blood samples were collected from patients in period between June to October 2016, chosen from Omdurman Maternal hospital (thirty of them used magnesium sulfate as supplement and thirty not used supplement) and sixty normal pregnant women as control. Serum sodium and potassium were measured by using ion selective electrode (Easylyte), while serum magnesium and serum calcium were measured by using Mindray 380 The study showed that, women with preeclampsia had significantly lowerlevels in means serum total calcium, magnesium, and potassium (7.34±0.51mg/dL) vs. (8.58± 0.71mg/dL) P<0.05, (1.29±0.23mmol/L) vs (1.83±0.32 mmol/L), and (3.08±0.24 mmol/L) vs 3.55±0.34 mmol/L) p value <0.05 respectively. There was significant increase in mean of serum sodium in women with preeclampsia compared to control group (144.57±3.93 mmol/L) vs (138.27±3.8 mmol/L) p value <0.05 There was significantly positive correlation between serum magnesium in preeclamptic women used magnesium sulfate and preeclamplic women not used magnesium sulfate ( r= 0.3 / p= 0,049), while there were weak negative correlations between serum calcium and potassium in these two groups.