25Mar 2017

POSTNATAL DEVEOPMENT OF BRUNNER'S GLAND IN RABBIT

  • Professor, Dept. of Anatomy, Pt. JNM Medical College, Raipur (C.G).
  • Retd. Professor and HOD Dept. of Anatomy G.R. Medical College,Gwalior (M.P.)
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Introduction- Brunner's glands are located in the submucosa of the duodenum in all mammals. The principal function of the glands is thought to be protection of the duodenal mucosa against the erosive effects of the gastric juice by virtue of the mucoid nature of its secretion,its alkalinity, and possibly by the buffering capacity of its bicarbonate content In the present study postnatal development of Brunner's glands in the rabbit was observed in 21 rabbits Material & methods- This research work was done during the period between1977-1979 as a part of thesis work. The present work, postnatal development of the duodenal submucosal glands in the four parts of the duodenum was studied in rabbit. Method-For postnatal developmental study of Brunner's glands in rabbit animals were used either the littermates or the young ones of the same parents. Rabbits of 0hrs, 1 week,2weeks,3weeks,4 weeks,5weeks, and 6 weeks age formed one series. Three such series were examined .Four pieces were taken from first, second, third and fourth part of duodenum and placed in fixative 10% formal saline . Tissues were processed routinely and stained with : haematoxylin and eosin for light microscopy. Results- The origin and development of Brunner's glands in the rabbit have been studied in postnatal animals. Brunner's glands arise principally from the bases of crypts of Lieberkuhn. The glands commence as buds which proliferate deep into the submucosa and branch to give rise to tubules and to a duct system. The Brunner's glands in rabbit extended up to the second part of duodenum at birth and their extent gradually increased distally By the end of second week the glandular tissue reached the fourth part of duodenum .The glands were more in the proximal part of duodenum and decreased from the proximal to the distal part .Compactness of glands when traced at weekly intervals in the identical parts of duodenum showed marked increase upto sixth week.The serous cells were differentiated in the terminal portions of tubules at birth but mucous acini started differentiated only after two weeks

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[Meena Goyal and K. Pandher. (2017); POSTNATAL DEVEOPMENT OF BRUNNER'S GLAND IN RABBIT Int. J. of Adv. Res. 5 (Mar). 868-876] (ISSN 2320-5407). www.journalijar.com

DR. MRS. MEENA GOYAL
Professor,Dept of Anatomy, Pt JNM Medical Collgege

DOI:

Article DOI: 10.21474/IJAR01/3583      
DOI URL: https://dx.doi.org/10.21474/IJAR01/3583

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