27Mar 2017

A PROSPECTIVE STUDY OF FACTORS RELATED TO PLATELET YIELD AMONG DONORS UNDERGOING PLATELETPHERSIS.

  • Senior Resident, Department of Transfusion Medicine, SKIMS, Srinagar, Jammu and Kashmir, India.
  • Additional Professor, Pediatric Hematology and Head Department of Blood Transfusion and Immunohematology, SKIMS, Srinagar, Jammu and Kashmir, India.
  • Senior Resident, Department of Transfusion Medicine, SKIMS, Srinagar, Jammu and Kashmir, India.
  • Scholars, Department of Transfusion Medicine, SKIMS, Srinagar,Jammu and Kashmir, India.
  • Junior Resident, Department of Transfusion Medicine, SKIMS, Srinagar, Jammu and Kashmir,India.
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Background: The transfusion of blood products is life saving especially at emergency conditions. The platelet transfusions helps in prevention of bleeding related complications and thus prevents morbidity and mortality in thrombocytopenic patients. Platelets are transfused by two methods i) by fractionation of whole blood and ii) by platelet apheresis. The quality of single donor platelets (SDP) in terms of yield influences platelet recovery in the recipient. Material and Methods: A sample of 360 donors were included in the study over a period of one and half year. Various donor-related factors were meticulously recorded prior to performing plateletpheresis. The aim was to identify donor factors that influence platelet yield. The plateletpheresis procedures were performed using Trima accel machine. A relationship between pre-donation donor variables and yield of platelets was studied using the Pearson correlation. Results: The mean platelet yield was 2.29 ± 0.43 x105/?L per donor. A positive correlation was observed between platelet yield and pre-donation platelet count, body mass index (BMI; Kg/m2) of the donor, while a negative correlation was observed between age and the platelet yield. Conclusion: Donor pre-donation platelet count, BMI and donor age influence platelet yield. Young healthy donors with a high platelet count and better BMI can give a better platelet yield in the SDP.

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[Irfan khan, Aleem Jan, Arshad Hassan Siddique, Arouj-bin-rashid, Zakir Bhat, Naira Firdous Zargar , Sehar kenu and Jaiparam singh wazir. (2017); A PROSPECTIVE STUDY OF FACTORS RELATED TO PLATELET YIELD AMONG DONORS UNDERGOING PLATELETPHERSIS. Int. J. of Adv. Res. 5 (Mar). 1051-1054] (ISSN 2320-5407). www.journalijar.com

Irfan khan
Skims soura

DOI:

Article DOI: 10.21474/IJAR01/3604      
DOI URL: https://dx.doi.org/10.21474/IJAR01/3604

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