Study the effectiveness of Artemisia herba-alba leaves extract on the experimental infection with Candida albicans isolated from urogenital tract in cows

This research aimed to study the effectiveness of Artemsiaherba-alba as a medicinal plant against Candida albicans isolated from urogenital tract in cows and used in the treatment of experimental infection in mice (in vivo) as well as determining the effect of alcoholic extract of this plant (in vitro) against same isolated pathogenic yeast by Minimum inhibitory concentration test. Artemisia herba-alba alcoholic extract was used in a dose 1mg/Kg.B.wt and 2mg/Kg.B.wt for one time when inducing the infection by Candida albicans in mice, extract of Artemisia herba-alba was able to cause significant decrease in the clinical signs as well as in reducing the post mortem changes that appear in very clear picture in the mice infected with Candida albicans alone, also Artemisia herba alba extract participated in the significant reduction in the numbers of Candida albicans colonies isolated from kidney and uterus of mice treated with Artemisia herba alba extract, the results of (fungal isolation) was supported by examining the ability of Artemisia herba-alba extract to inhibit Candida albicans growth in vitro by determining minimum inhibitory concentration (MIC).