The benefits of Surfactant and Continuous Positive Airway Pressure in Premature newborns

• Background: Neonatal respiratory distress is a serious clinical problem associated with high morbidity and mortality, and different strategies applied for treatment of respiratory distress syndrome composed of surfactant, CPAP, both of them or nill treatment. • Objective: To investigate the benefits and outcome Application of surfactant and Continuous Positive Airway Pressure (CPAP) in the neonate with respiratory distress admitted to nursery care unit. • Patients and Methods : This retrospective clinical study was performed on 294 preterm neonates who were admitted to the neonatal nursery care unit of Madinat Al-Imamin Al-Kademain Teaching Hospital because of respiratory distress from the 1st January 2012 to thirty 1st of December 2012. The information taken regarding gender , gestational age , birth weight , which treatment given,and its outcome according to the treatment given . • Result: During the study period of 294 premature with RDS the surfactant ,CPAP , Both of them or Nill treatment have demographic characteristics , 12 (4%) patients received the Surfactant therapy proved to be effective in the 9 cases (75%) cases received it , CPAP given to 101 (34%) of cases and was effective in 64( 63% )of patients , while the 53(18%) received Both surfactant and CPAP it was effective in 29(55%) and in the rest 128(44%) of cases that didn’t receive any kind of treatment it was effective in 79(61%) of patients. Estimated survival rates at 24 hours in surfactant , Continuous Positive Airway Pressure, Both of surfactant , Continuous Positive Airway Pressure and Nill treatment groups were 100% ,77%,100% and 35% respectively. • Conclusion: According to the results, surfactant and Both of surfactant , Continuous Positive Airway Pressure were effective in the treatment of neonates who were suffering from respiratory distress syndrome.