25Apr 2017

ANTIMICROBIAL ACTIVITIES OF SILVER NANOPARTICLES SYNTHESIZED FROM CISSUS QUADRANGULARIS PLANT EXTRACT.

  • Assistant Professor, Department of PG Biochemistry, V.V.Vanniaperumal College for Women, Virudhunagar-626001, Tamilnadu, India.
  • Research Scholar, Department of Biochemistry, University of Madras, Chennai, Tamilnadu, India.
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Cissus quadrangularis is one among the most frequently used medicinal plants in India which can be found throughout the country. The present investigation was focused with much attention to investigate the phytochemical constituents, antimicrobial activity of Cissus quadrangularis silver nanoparticles. The synthesized nanoparticles of the plant Cissus quadrangularis were characterized by UV-VIS spectrophotometer and FTIR .The antimicrobial activity of Cissus quadrangularis nanoparticles was performed with disc diffusion method. The biosynthesis of silver nanoparticles (AgNPs) was initially detected by the color change of the solution from light yellow to honey brown. UV-Vis spectra of synthesized AgNPs which give a sharp band at around 430 nm and confirmed the synthesis of AgNPs. The FTIR analysis of synthesized nanoparticles from Cissus quadranguaris revealed prominent peaks at 1631.52 cm-1, 2147.12 cm-1 and 3370.56 cm-1 corresponds to N-H bending of primary amines. The absorption peaks obtained at 2146 cm1 assigned to ?C≡C˗ stretching of alkynes. The phytochemical screening of the Cissus quadrangularis nanoparticles revealed the presence of flavonoids, proteins, alkaloids, phenols, carbohydrates and terpenoids. The antimicrobial activity of C.quadrangularis was found to be very effective against S.aureus with a maximum zone of inhibition with 26 mm in diameter. The silver nanoparticles obtained from Cissus quadrangularis exhibited significant antimicrobial activities without any serious side effects. These findings clearly demonstrated that the bioactive metabolites present in Cissus quadrangularis can be used for the treatment of disease.

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[Sudha Rameshwari. K and Maheshwari. V. (2017); ANTIMICROBIAL ACTIVITIES OF SILVER NANOPARTICLES SYNTHESIZED FROM CISSUS QUADRANGULARIS PLANT EXTRACT. Int. J. of Adv. Res. 5 (Apr). 1171-1177] (ISSN 2320-5407). www.journalijar.com

SUDHA RAMESHWARI.K*
V.V.Vanniaperumal College for Women, Virudhunagar-626001, Tamilnadu, India.

DOI:

Article DOI: 10.21474/IJAR01/3930      
DOI URL: https://dx.doi.org/10.21474/IJAR01/3930

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