PHENYTOIN AND SODIUM VALPROATE INTOXICATION AND MANAGEMENT, A CASE REPORT
Surya Prakash Yarramalle
, Kartik Munta
, S. Manimala Rao
, Hemanth. C
, Dhanalakshmi
and Sohal Parate.
- Department Of Critical Care Medicine, Yashoda Multi-Speciality Hospital, Somajiguda, Hyderabad, India.
- Department Of General Medicine, Yashoda Multi-Speciality Hospital, Somajiguda, Hyderabad, India
- Department Of Nephrology, Yashoda Multi-Speciality Hospital, Somajiguda, Hyderabad, India.
- Abstract
- Keywords
- References
- Cite This Article as
- Corresponding Author
Phenytoin Toxicity Is Challenging Due To Its Pharmacokinetic Properties And Narrow Therapeutic Index. Serum Values In Valproate Toxicity Do Not Correlate With Its Side Effects. In This Case Report, Patient Consumed 100 Tablets Of Phenytoin And 15 Tablets Of Sodium Valproate Causing Her Serum Levels Of Phenytoin And Valproate Rise To 100mcg/Ml And 1.4mcg/Ml Respectively. Her Conditioned Worsened And Suffered Cardiac Arrest On 9th Day Of Admission During Supportive Therapy. Plasma Pheresis Was Done As Rescue Measure Which Decreased Phenytoin Levels. Her Neurological Condition Improved And Was Discharged After 40 Days Of Hospital Stay.
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[Surya Prakash Yarramalle, Kartik Munta, S. Manimala Rao, Hemanth. C, Dhanalakshmi and Sohal Parate. (2017); PHENYTOIN AND SODIUM VALPROATE INTOXICATION AND MANAGEMENT, A CASE REPORT Int. J. of Adv. Res. 5 (Apr). 1610-1621] (ISSN 2320-5407). www.journalijar.com
