ASYMPTOMATIC BACTERIURIAIN NORMAL PREGNANCY.

- Microbiologist,TSMU The First University Clinic,MD,PhD(Tbilisi,Georgia).
- Head of DepartmentofObstetrics and Gynecology,TSMU Professor(Tbilisi,Georgia).
- Headof clinical laboratory,TSMU The First University Clinic,MD,PhD(Tbilisi, Georgia).
- TSMU Department of Obstetrics and Gynecology,Assistant professor,MD,PhD(Tbilisi,Georgia).
- TSMU Department of Obstetrics and Gynecology, MD, PhD,(Tbilisi, Georgia).
- Abstract
- Keywords
- References
- Cite This Article as
- Corresponding Author
The prevalence of asymptomatic bacteriuria (ASB) in pregnant women is 2% to 10%and depends on race, parity, and socioeconomic status . Escherichia coli is the most common etiologic agent in asymptomatic infection and quantitative culture is the gold standard for diagnosis.In pregnant women this infection can progress upward, causing acute urethritis, acute cystitis(40%), and acute pyelonephritis (25-30%). Pyelonephritis, in turn, can lead to adverse outcomes such as preterm labor, which is the most common cause of serious complications-including death-in newborn babies. A positive urine culture is the only means of diagnosis. The U.S. preventive service task force and American Congress of Obstetricians and Gynecologists most strongly recommend screening and treating for asymptomatic bacteriuria (ASB) in pregnant women. Weretrospectivelyhave studied frequency and microbial spectrum of asymptomaticbacteriuria in pregnant women without clinical demonstrationswith gestational age of 12-16 weeks who visited TSMU The First University Clinic obstetrics and gynecology department in 2015-2016.Our results showed that the prevalence of asymptomatic bacteriuria in normal pregnant women is 9.3% ,which is approximately the same as the other countries(2-10%). However, more studies are required to determine the specific rate of asymptomatic bacteriuria and factors that are responsible for region differences.Escherichia coliwas the most common isolate accounting for approximately 53,8% of cases. It originates from fecal flora colonizing
- Hooton TM, Roberts PL, Cox ME, Stapleton AE. Voided midstream urine culture and acute cystitis in premenopausal women. N Engl J Med 2013;
- Widmer M, Lopez I, G?lmezoglu AM, et al. Duration of treatment for asymptomatic bacteriuria during pregnancy. Cochrane Database Syst Rev 2015;
- Hooton TM, Roberts PL, Cox ME, Stapleton AE. Voided midstream urine culture and acute cystitis in premenopausal women. N Engl J Med 2013; 369:1883.
- Gupta K, Hooton TM, Naber KG, et al. International clinical practice guidelines for the treatment of acute uncomplicated cystitis and pyelonephritis in women: A 2010 update by the Infectious Diseases Society of America and the European Society for Microbiology and Infectious Diseases. Clin Infect Dis 2011; 52:e103.
- Vazquez JC, Abalos E. Treatments for symptomatic urinary tract infections during pregnancy. Cochrane Database Syst Rev 2011; :CD002256.
- Gomi H, Goto Y, Laopaiboon M, et al. Routine blood cultures in the management of pyelonephritis in pregnancy for improving outcomes. Cochrane Database Syst Rev 2015; :CD009216.
- Albright CM, Ali TN, Lopes V, et al. Lactic acid measurement to identify risk of morbidity from sepsis in pregnancy. Am J Perinatol 2015; 32:481.
- Keating GM. Fosfomycintrometamol: a review of its use as a single-dose oral treatment for patients with acute lower urinary tract infections and pregnant women with asymptomatic bacteriuria. Drugs 2013; 73:1951.
- Urinary Tract Infection". April 17, 2015. Retrieved?9 February?2016.
- Flores-Mireles, AL; Walker, JN; Caparon, M; Hultgren, SJ (May 2015).
- Goldstein, I; Dicks, B; Kim, NN; Hartzell, R (December 2013). "Multidisciplinary overview of vaginal atrophy and associated genitourinary symptoms in postmenopausal women.".Sexual medicine.?1?(2):
- Colgan, R; Nicolle, LE; McGlone, A; Hooton, TM (Sep 15, 2006). "Asymptomatic bacteriuria in adults.".American family physician.?74?(6): 985?9.
[Tamar Didbaridze, AleksandreTharashvili2, Nino Gogokhia, Nato Metskhvarishvili and Maia Rizhvadze. (2017); ASYMPTOMATIC BACTERIURIAIN NORMAL PREGNANCY. Int. J. of Adv. Res. 5 (May). 535-537] (ISSN 2320-5407). www.journalijar.com