NORMAL REFERENCE RANGES FOR SERUM URIC ACID IN POPULATION OF NORTH BIHAR
- Assistant Professor, Department of Pathology, Darbhanga Medical College, Darbhanga.Tutor, AIIMS, Patna.
- Senior Resident, Department of surgery, Darbhanga Medical College, Darbhanga.
- Professor and H.O.D, Department of Pathology, Darbhanga Medical College, Darbhanga.
- Abstract
- References
- Cite This Article as
- Corresponding Author
Aim: To establish the reference range of serum uric acid levels in this population among healthy individuals. Design: Prospective study done at Darbhanga Medical College, Bihar from December 2006- January 2009. Materials and Methods: 1000 individuals above 30 years of age were included in the study. There were equal no of males and females.55%(n=550) were vegetarians and 45%(n=450) were non vegetarians.45%(n=450) were of low socioeconomic group,40%(n=400)were of middle socioeconomic group and 15%(n=150) were of high socioeconomic group.70.2%(n=702) were of normal weight,19.8%(n=198) were overweight,5.3%(n=53) were underweight and 3.7%(n=37) were obese. Serum uric acid was estimated by modified phototungstate method, end point assay. The values of serum uric acid were statistically analyzed in relation to age, sex, BMI, socio economic group and eating habits. Results:- ? The observed reference range of uric acid in the population in male is 3.5-6.5mg% and in females is 2.5-6mg%. ? The mean serum uric acid in males was 4.959 ?1.029 and in females 3.99 ? 1.042.There is significant difference (t=11.07,p<0.001) ? Mean serum uric acid in non vegetarians was slightly higher than vegetarians but not significant(t=1.48,p>0.05) ? Serum uric acid was significantly higher in overweight and obese (t=11.07), p<0.001) in comparison to underweight and normal weight. ? Serum uric acid was higher in high socioeconomic strata compared to low socioeconomic group (t=10.42, p<0.001).
- Prevalence of Gout and Hyperuricaemia in the US General Population The National Health and Nutrition Examination Survey 2007?2008 Yanyan Zhu,1 Bhavik J. Pandya,2 and Hyon K. Choi1
- Medscape, an online website
- D. Gardner and R. Scott, ?Age- and sex-related reference ranges for eight plasma constituents derived from randomly selected adults in a Scottish new town,? Journal of Clinical Pathology, vol. 33, no. 4, pp. 380?385, 1980.
- H. Reed, D. C. Cannon, J. W. Winkelman, Y. P. Bhasin, R. J. Henry, and V. J. Pileggi, ?Estimation of normal ranges from a controlled sample survey. I. Sex- and age-related influence on the SMA 12-60 screening group of tests,? Clinical Chemistry, vol. 18, no. 1, pp. 57?66, 1972.
- Bengtsson and E. Tibblin, ?Serum uric acid levels in women: an epidemiological survey with special reference to women with high serum uric acid values,?ActaMedicaScandinavica, vol. 196, no. 1-2, pp. 93?102, 1974
- Das M, Saikia M. Estimation of lipid profile in Assamese population. Indian Journal of Clinical Biochemistry, 2009; 24 (2) 190-193.
- Dybkaer and R. Grsbeck, ?Theory of reference values,? Scandinavian Journal of Clinical & Laboratory Investigation, vol. 32, pp. 1?7, 1973.
- Madhumita Das, C. Borah,?M. Ghose,?and?N. Choudhury-Reference Ranges for Serum Uric Acid among Healthy Assamese PeopleS.
- Winsten, ?The ecology of normal values in clinical chemistry,? CRC Critical Reviews in Clinical Laboratory Sciences, vol. 6, no. 4, pp. 319?330, 1976.
- Alimonti, B. Bocca, E. Mannella et al., ?Assessment of reference values for selected elements in a healthy urban population,? Annalidell?IstitutoSuperiore di Sanita, vol. 41, no. 2, pp. 181?187, 2005.
[Talat Fatma, Nishi, Shamim Khurrum Azmi and Ajit Kumar Chaudhary. (2017); NORMAL REFERENCE RANGES FOR SERUM URIC ACID IN POPULATION OF NORTH BIHAR Int. J. of Adv. Res. 5 (May). 682-686] (ISSN 2320-5407). www.journalijar.com
M.B.B.S, M.D
