10Aug 2017

THE EFFICACY OF STRONTIUM RANELATE IN THE MANAGEMENT OF ALVEOLAR BONE LOSS (CLINICAL AND RADIOGRAPHIC STUDY).

  • Professor of Oral medicine and Pereiodontology, Department of Oral medicine and periodontology, Faculty of Oral and Dental Medicine, Mansuora university, Egypt.
  • B.D.S, Faculty of Oral and Dental Medicine, Mansuora university, Egypt.
  • Lecturer of Oral medicine and Pereiodontology, Department of Oral medicine and periodontology, Faculty of Oral and Dental Medicine, Mansuora university, Egypt.
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Objective: The aim of the present study is to evaluate the efficacy of strontium ranelate as a bone graft substance in correction of alveolar bone loss associated with periodontal disease . Materials and methods: A split-mouth study were used in 20 patients suffering from periodontal disease with alveolar bone loss. After scalling, root planning (SRP) and depridement of granulation tissue in the depth of the periodontal pocket , a full thickness flap was done and a mix of strontium ranelate 2gm (Protelos) with sterile saline was delivered in a putty form on the alveolar bone untill the bone defect is filled, and the other side was subjected only to SRP and depridement of granulation tissue.At first Periodontal health statue will be assessed by measuring specific indices such as: Gingval index (GI), Periodontal pocket depth (PPD) ,Bleeding on probing (BOP) and Plaque index (PI). At baseline, digital panoramic radiograph was taken, patients were recalled for follow up and rescoring of all indices after 2, 6 and 8 weeks, and a panoramic radiographs were taken again after 12 weeks for radiographic assesement . Results: Comparing the PPD between the 2 sides showed that there was much improvement in the scores in the side of the strontium ranelate(applied side) and (p value <0.05) , so the difference between 2 sides considered statistically significant. Panoramic xrays results: comparing two sides showed increase nearly about0.5-1.1 mm in the hight of the alveloar bone in the side of strontium ranelate (applied side) while the other side(control side) remained without any progression in the height of the alveolar bone. Conclusion: clinical and radiographic results obviously showed statistically significant and provides evidence that strontium ranelate can be used for management of alveolar bone loss assiociated with periodontal diseases.

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[Omar H. khashaba, A. Nabil Nasser and M. M. Bazed. (2017); THE EFFICACY OF STRONTIUM RANELATE IN THE MANAGEMENT OF ALVEOLAR BONE LOSS (CLINICAL AND RADIOGRAPHIC STUDY). Int. J. of Adv. Res. 5 (Aug). 50-63] (ISSN 2320-5407). www.journalijar.com

ahmed nasser

DOI:

Article DOI: 10.21474/IJAR01/5034      
DOI URL: https://dx.doi.org/10.21474/IJAR01/5034

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