ASSESSMENT OF MAGNESIUM AND PHOSPHORUS IN SUDANESE ALCOHOLISM IN KHARTOUM STATE.

Alcoholism is a major issue globally. It is estimated to be the fifth leading risk factor for global disability-adjusted life years. Commonly chronic alcoholic patients develop a variety of acid base and electrolyte disturbances, which play a significant role in their morbidity and mortality. Physicians should recognize these abnormalities and the underlying interrelated patho-physiological mechanisms for their prompt diagnosis and appropriate management. This study was carried out to measure serum levels of the magnesium and Phosphorus in Sudanese alcoholism. A total of one hundred and twenty subjects were enrolled in this study, divided into two groups sixty alcoholism and sixty normal individual serve as control were collected from period between May to June 2017, chosen randomly from Khartoum state , to assess the blood levels of magnesium and phosphorus. Serum magnesium and Phosphorus were measured by using full automated chemical analyzer BS 380 and results were analyzed using statistical of package social science (SPSS), computer program. The study showed that, alcoholism had significantly decreased the means of serum magnesium and phosphorus (3..91?0.39mg/dl) vs. (5.34?0.68 mg/dL) P<0.05, (2.48?0.71 mg/dl) vs (4.32?0.66 mg/dl) p value <0.05 respectively . There were significantly weak negative correlation between serum magnesium, phosphorus levels and duration of alcoholism (r=-0.264 , p value=0.041), (r = − 0.034 , P, value = 0.008 ) respectively and there was insignificant weak positive correlation between serum magnesium in alcoholism and age (r = 0.214 and P, value= 0.089 ) while there was insignificant weak negative correlation between serum phosphorus in alcoholism and age (r = − 0.097 and P = 0.460). The study concluded that, the level of magnesium and phosphorus were significantly decreased in alcoholism.