22Aug 2017

PRELIMINARY PHYTOCHEMICAL SCREENING AND ANTIBACTERIAL ACTIVITY OF INDIAN MEDICINAL PLANTS AGAINST HUMAN PATHOGENS.

  • Research Scholar, Microbiology Department, B. P. Baria Science Institute, Navsari-396445, India.
  • Associate Professor, Microbiology Department, B. P. Baria Science Institute, Navsari-396445, India.
  • Abstract
  • Keywords
  • References
  • Cite This Article as
  • Corresponding Author

Antibacterial efficiency of leaf extract of Flacourtia indica, Eujenia jambulaand Citrus sinensis were examined using Methanol as solvent and tested against the following five human pathogens: Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, Klebsiella pneumoniae and Salmonella typhi using agar well diffusion method. All the plants showed significant activity against the test pathogens except Klebsiella species. The methanolic extract of all three plants showed maximum zone of inhibition against Staphylococcus aureus and Salmonella typhi as compared to other organisms.


  1. Bauer AW et al. (1966); Antibiotic susceptibility testing by standardize single disc or cup method; Amer. J. Clini. Path., 45(4): 493-496.
  2. Denis O, Eliakim M, Godfrey M, David K, Geoffrey O (2015); Antimicrobial activity of Eugenia jambulana seeds against footborne isolates; Journal of Scientific &Innovative Research, 4(6): 232-236.
  3. Gayathri D, Eramma N (2013); Antibacterial potential and phytochemical analysis of Flacourtiaindica (Burm.f.) Merr. root extract against human pathogens; Indo American Journal of Pharmaceutical Research, 3(5): 3832-3846.
  4. Grosso G, Galvano F, Mistretta A, Marventano S, Nolfo F, Calabrese (2013); G. Red orange: experimental models and epidemiological evidence of its benefits on human health; Oxid Med Cell Longev.? 2013:157240.
  5. Hajra S, Mehta A, Pandey P (2011); Assessment of antimicrobial activity of Cassia fistula and Flacourtiaindica leaves; J Pharm Res., 4(7): 2432-2435.
  6. Keeling C, Bohlmann J (2006); Genes, enzymes, and chemicals of terpenoid diversity in the constitutive and induced defence of conifers against insects and pathogens; New Phytologist; 170:657-675.
  7. Kirtikar K, Basu B (1933); Indian medicinal plants. New Delhi: Bishen Singh Mahendra Pal Singh, 1(2): 220-222.
  8. Kota G, Karthikeyan M, Kannan M (2012); Flacourtiaindica (Burm. f.) Merr.-A. Phytopharmacological Review; Int. J Res Pharmaceut Biomed Sci., 3(1), 78-81.
  9. Lachumy S, Sreenivasan S, Vello S, Zakaria Z (2010); Pharmacological activity, phytochemical analysis and toxicity of methanol extract of Etlingeraelatior (torch ginger) flowers; Asian Pacific Journal of Tropical Medicine. 3(10): 769-774.
  10. Mamta K, Sulbha L, Prabhakar V, Sudhir R, Suresh R, Shailendra G (2011); Anti-Inflammatory and Antimicrobial activity of FlacourtiaRamontchi Leaves; International Journal of Drug Development & Research. 3(2): 308-313.
  11. Minocheherhomji FP, Vyas BM (2014); Presence of Alkaloids in medicinal plants and their importance in antimicrobial activities on some pathogenic microbial strains; Journal of Environmental Research & Development, 9(1): 144-150.
  12. Ram P, Seamy V, Suranjit P, Ajit V (2012); Biogenic synthesis of silver nanoparticles from the leaf extract of Syzygiumcumini (L.).; International journal of pharma and biosciences. 3(4): 745-752.
  13. Shakthi A, Sathish T, Kumaresan K, Rapheal V (2014); Extraction process optimization of polyphenols from Indian Citrus sinensis - as novel antiglycative agents in the management of diabetes mellitus;?J Diabetes MetabDisord. 13:11.
  14. Suja D, Bupesh G, Nivya R, Mohan V, Ramasamy P, Muthiah N, Arul A, Meenakumari K, Prabu K (2017); Phytochemical Screening, Antioxidant, Antibacterial Activities of Citrus Limon and Citrus Sinensis Peel Extracts; International Journal of Pharmacognosy and Chinese Medicine. 1(2): 1-7.
  15. Vennila S, Bupesh G, Mathiyazhagan K, Basker M, Amutha S (2012); Qualitative phytochemical Screening and Invitro antioxidant activity of H.isora.; Adv Biotech J 14: 3-20.
  16. Visweswari G, Rita C, Rajendra W (2013); Phytochemical screening of active secondary metabolites present in WithaniaSomnifera root: role in traditional medicine; International journal of pharmaceutical sciences and research. 4(7): 2770-2776.
  17. Vogel H (1991); Similarities between various systems of traditional medicine. Considerations for the future of ethnopharmacology; J. Ethnopharma col. 35: 179-190.
  18. Zwenger S, Basu C (2008); Plant terpenoids: applications and potentials; Biotechnology and Molecular Biology Reviews. 3:001-007.

[Margi H. Patel and Farida P. Minocheherhomji. (2017); PRELIMINARY PHYTOCHEMICAL SCREENING AND ANTIBACTERIAL ACTIVITY OF INDIAN MEDICINAL PLANTS AGAINST HUMAN PATHOGENS. Int. J. of Adv. Res. 5 (Aug). 1459-1464] (ISSN 2320-5407). www.journalijar.com


Farida P. Minocheherhomji
Associate-Professor, Microbiology Department, B. P. Baria Science Institute, NAVSARI - 396445, Gujarat, India.

DOI:


Article DOI: 10.21474/IJAR01/5204      
DOI URL: https://dx.doi.org/10.21474/IJAR01/5204