20Nov 2017

EFFECTS OF SILYMARIN PLUS VERSUS ANTIBIOTICS ON IMPROVING IDIOPATHIC POOR CONCEPTION AND PREGNANCY RATES OF MARES.

  • Department of Theriogenology, Faculty of Veterinary Medicine, Benha University, P.O:13736, Tokh, Kaliobia, Egypt.
  • Department of physiology Faculty of Veterinary Medicine, Benha University, P.O: 13736, Tokh, Kaliobia, Egypt.
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The current study was carried out to investigate the improving roles of silymarin-plus? versus antibiotics on mare?s uterine environment quality (UEQ). Current study was carried on 23 mares aged between 7-13y. Animals were subjected to clinical and gynecological examinations with detailed breeding history that revealed repeat breeding although there were apparently normal mares with normal breeding management. Animals were divided into three groups according to medications used in lavage; G1 (Silymarin-plus?), G2 (Ciprofloxacin + Amikacin), and G3 (mixture between Silymarin plus? and Ciprofloxacin + Amikacin). Jugular blood samples were collected to assess the hormonal patterns (E2 & P4) in correlation with monitoring UEQ and follicular growth by ultrasonography. There was non-significant difference (P<0.05) between groups concerning the conception rate although G1 and G3 having the highest conception rate. There was highly significant difference (P<0.05) between groups regarding the pregnancy rate. Moreover, there were non-significant difference between the treatment groups concerning both follicular growth and E2 and P4 levels. Ultrasonography images for silymarin plus? treated groups only revealed presence of unpleasant hyperechoic fine particles that faded on subsequent uterine washing times and before the suspected day of ovulation, where on day 4 of estrus period the washing fluid is totally anechoic. Fine particles in the first uterine lavages were suspected to negatively affect UEQ. On conclusion: Silymarin plus? incorporation in the uterine lavage solution for mares is helpful to improve their pregnancy rate; especially those with idiopathic causes of repeat breeding. Silymarin plus? might have a great role in improving UEQ.

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[Mohamed El-Raey and Rasha E. Azab. (2017); EFFECTS OF SILYMARIN PLUS VERSUS ANTIBIOTICS ON IMPROVING IDIOPATHIC POOR CONCEPTION AND PREGNANCY RATES OF MARES. Int. J. of Adv. Res. 5 (Nov). 927-941] (ISSN 2320-5407). www.journalijar.com

Mohamed El-Raey Mohamed Metwalli
Lecturer of Theriogenology, Faculty of Veterinary Medicine, Benha University

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Article DOI: 10.21474/IJAR01/5851      
DOI URL: https://dx.doi.org/10.21474/IJAR01/5851

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