PUBLIC USAGE OF ISOTRETINOIN IN SAUDI ARABIA: AN ONLINE SURVEY.

  • Medical intern, Faculty of Medicine, King Abdulaziz University, Saudi Arabia.
  • Department of dermatology, Faculty of Medicine, King Abdulaziz University, Saudi Arabia.
  • Abstract
  • Keywords
  • References
  • Cite This Article as
  • Corresponding Author

Isotretinoin (Roaccutane) is an effective medication for acne treatment. It has side effects and the main concern is its teratogenic effect. It has to be prescribed and followed up by dermatologists. In this study the public use of this medication is explored through an online questionnaire. Out of 401 respondents, 154 have used Roaccutane. Thirty one respondents have used it without medical consultation. These included females of childbearing age. Sources of recommendation of medication included pharmacists, friends, relatives and others. This warrants more rigorous restriction on its dispensing and public awareness efforts.


  1. AlGhamdi KM, Khurram H, Asiri YA, Mandil A (2011). Dermatologists' level of compliance with the prescription guidelines of isotretinoin for females of childbearing potential. Int J Dermatol. 50(9):1094-1098.
  2. Alrwisan AA, Alshammari TM, Tahir KW, Aleissa FM, Aljadhey HS (2014). Community pharmacists? knowledge of isotretinoin safety. Saudi Med J. Vol. 35 (1): 81-84
  3. BAD (British Association of dermatologists) clinical guidelines: http://www.bad.org.uk/ResourceListing.aspx?sitesectionid=678&itemid=254 accessed on 9/2/2017
  4. Cunliffe WJ, van de Kerkhof PC, Caputo R, Cavicchini S, Cooper A, Fyrand OL, Gollnick H, Layton AM, Leyden JJ, Mascar? JM, Ortonne JP, Shalita A (1997). Roaccutane treatment guidelines: results of an international survey. 194(4): 351-357.
  5. Gollnick HP, Zouboulis CC (2014). Not all acne is acne vulgaris. Dtsch Arztebl Int.111(17): 301-312.
  6. Lagan BM, Dolk H, White B, Uges DRA, Sinclair M (2014). Assessing the availability of the teratogenic drug isotretinoin outside the pregnancy prevention programme: a survey of e-pharmacies. Pharmacoepidemiol Drug Saf. 23(4): 411?418.
  7. Lammer EJ, Chen DT, Hoar RM, Agnish ND, Benke PJ, Braun JT, Curry CJ, Fernhoff PM, Grix AW Jr, Lott IT, et al. Retinoic acid embryopathy. N Engl J Med(1985). 1985 313: 837-841.
  8. Lee YH, Scharnitz TP, Muscat J, Chen A, Gupta-Elera G, Kirby JS (2016). Laboratory Monitoring during Isotretinoin therapy for acne: A systematic review and meta-analysis. JAMA Dermatol.152(1): 35-44.
  9. Nast A, Dr?no B, Bettoli V, Degitz K, Erdmann R, Finlay AY, Ganceviciene R, Haedersdal M, Layton A, L?pez-Estebaranz JL, Ochsendorf F, Oprica C, Rosumeck S, Rzany B, Sammain A, Simonart T, Veien NK, Zivković MV, Zouboulis CC, Gollnick H (2012). European Evidence-based (S3) Guidelines for the Treatment of Acne. J Eur Acad Dermatol Venereol. 26(s1): 1?29.
  10. US food and drug administration 2: iPLEDGE information: Most Recent Modification: 04/2012 RISK EVALUATION AND MITIGATION STRATEGY (REMS) The iPLEDGE Program Single Shared System for Isotretinoin: http://www.fda.gov/downloads/drugs/drugsafety/postmarketdrugsafetyinformationforpatientsandproviders/ucm234639.pdf Accessed on 8/2/2017
  11. US food and drug administration: iPLEDGE information: http://www.fda.gov/Drugs/DrugSafety/PostmarketDrugSafetyInformationforPatientsandProviders/ucm094307.htm. Accessed on 8/2/2017.

[Sarah K. Alharbi and Amal A. Kokandi. (2017); PUBLIC USAGE OF ISOTRETINOIN IN SAUDI ARABIA: AN ONLINE SURVEY. Int. J. of Adv. Res. 5 (Dec). 260-263] (ISSN 2320-5407). www.journalijar.com


Sarah K. alharbi
medical intern .king abdulaziz university

DOI:


Article DOI: 10.21474/IJAR01/5962      
DOI URL: https://dx.doi.org/10.21474/IJAR01/5962