Antioxidant and Anti-proliferative activity of methanolic leaf extract of Eupatorium glandulosum. L

From olden days it was believed that natural plants and its products have given the cure of every disease. Furthermore, plant extracts have been revealed to possess health-promoting properties. In the present study leaf extract of Eupatorium glandulosum was used to evaluate antioxidant (DPPH, metal chelating ions, hydroxyl radical, hydrogen peroxide, reducing power and nitric oxide radicals) and anti-proliferative properties. Powdered plant leaf was extracted with methanol solvent and tested for the antioxidant activity and analyzed for the result. The plant extract of E. glandulosum possessed the highest antioxidant activities in higher concentration (100 mg/ml). Anti-proliferative activity against mitogen induced lymphocytes using MTT assay showed the most potent activity. Plant extracts and plant-derived antioxidant compounds potentiate body’s antioxidant defense and are of choice because of their lower toxicity and side effects.