18Dec 2017

LUPUS PANNICULITIS IN A 12 YEAR OLD BOY: A CASE REPORT.

Crossref Cited-by Linking logo

  • Abstract
  • Keywords
  • References
  • Cite This Article as
  • Corresponding Author

Introduction: Lupus panniculitis, also known as Lupus profundus or subcutaneous Lupus erythematosus (LE), was first described by Kaposi in the year 1869. It is a small subset of all cutaneous LE which represents 2-3% of this group. It usually occurs in 3rd ? 4th decade but children can also develop lupus panniculitis. There is female preponderance with female: male ratio ranging from 2:1 to 4:1.1 Case report: A 12 year old boy presented with multiple painful , mildly erythematous to bluish coloured nodules over the face and upper arms, sparing the distal upper limbs for last six months. Cutaneous examination revealed multiple, mildly-tender, indurated erythematous to bluish coloured nodules over face & upper arms. ANA- 2.5 & anti-ds DNA- 200 IU/ml. Histopathological examination revealed mild pericapillary lymphocytic infiltration in dermis with deep subcutaneous fat showing moderatelymphohistiocytic cell infiltration with focal areas of necrosis and occasional ill-formed granulomas which was consistent with granulomatous panniculitis. Direct immunofluorescence (DIF) showed- deposits of IgG, IgM, IgA and C3 along the dermo-epidermal junction.

  1. Patterson JW. Panniculitis. In: Bolognia JL, Jorizzo JL, Schaffer JV, editors. Textbook of Dermatology. 3rd China : Elsevier Saunders; 2012. p. 1303-19.
  2. Martens PB, Moder KG, Ahmed I. Lupus panniculitis: clinical perspectives from a case series. The Journal of rheumatology. 1999 Jan;26(1):68-72.
  3. Koley S, Sarkar J, Choudhary SV, Choudhury M, Banerjee G, Bar C, Chatterjee T. Lupus erythematosus panniculitis: a case report. Journal of Pakistan Association of Dermatology. 2016 Dec 22;21(2):118-21.
  4. Winfield H, Jaworsky C. Connective tissue diseases. In: Elder DE, editor-in-chief. Lever?s histopathology of the skin. 10th China: Lippincott Williams and Wilkins; 2009. p. 279-310.
  5. Bednarek A, Bartoszak L, Samborski W. Case report on a patient with lupus panniculitis. Advances in Dermatology and Allergology/PostȩpyDermatologii i Alergologii. 2015 Feb;32(1):59.
  6. David-Bajar KM, Bennion SD, DeSpain JD, et al. Clinical, histologic, and immunofluorescent distinctions between subacute cutaneous lupus erythematosus and discoid lupus erythematosus. J Invest Dermatol. 1992;99:251?7.
  7. Winkelmann RR, Kim GK, Del Rosso JQ. Treatment of cutaneous lupus erythematosus: review and assessment of treatment benefits based on Oxford Centre for Evidence-Based Medicine criteria. The Journal of clinical and aesthetic dermatology. 2013 Jan;6(1):27.
  8. Dhaou BB, Aydi Z, Rachdi I, Hammami H, Daoud F, Brahim EB, Fenniche S, Debbiche A, Boussema F. Lupus erythematosuspanniculitis: A case report. Journal of Dermatology & Dermatologic Surgery. 2016 Nov 16.

[Romita Bachaspatimayum, Y. Imlongchaba, Anup Goswami and Angila Dorjee. (2017); LUPUS PANNICULITIS IN A 12 YEAR OLD BOY: A CASE REPORT. Int. J. of Adv. Res. 5 (Dec). 987-990] (ISSN 2320-5407). www.journalijar.com

Anup Goswami
Post Graduate Trainee

DOI:

Article DOI: 10.21474/IJAR01/6047      
DOI URL: https://dx.doi.org/10.21474/IJAR01/6047

Download Full Paper

Download PDF No. of Downloads: 20 | No. of Views: 127